Establishment of effective cure of melatonin for severe stomatitis

• Project/Area Number: 22791984
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Surgical dentistry
• Research Institution: The University of Tokushima
• Principal Investigator: KUDOH Keiko 徳島大学, ヘルスバイオサイエンス研究部, 助教 (70380029)
• Project Period (FY): 2010-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: メラトニン / 口内炎 / 口腔がん

Research Abstract

In this study, it was intended that I examined the effectiveness of melatonin for severe stomatitis to occur with chemotherapy of oral cancer and radiotherapy. I examined the action as a prevention for stomatitis of melatonin, a progress suppressant or the therapeutic drug. I was able to suggest the possibility that melatonin helped the side effect reduction in the oral cancer treatment by these findings.