Heat hyperalgesia in mice model of burning mouth syndrome

• Project/Area Number: 22792021
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Surgical dentistry
• Research Institution: Nihon University
• Principal Investigator: SHINODA Masamichi 日本大学, 歯学部, 准教授 (20362238)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 口腔外科学一般 / 舌痛症 / TRPV1 / Artemin / GFRα3

Research Abstract

We established burning mouth syndrome model induce by TNBS treatment on tongue in mouse. The results indicated that Artemin-GFR. 3 signaling plays an important role in tongue thermal hyperalgesia caused by TNBS administration on tongue.

Research Products

• [Journal Article] Peripheral and Central Mechanisms of Trigeminal Neuropathic and Inflammatory Pain (2011)
  • Author(s): Takeda M, Matsumoto S. Sessle BJ. Shinoda M, Iwata K.
  • Journal Title: J. Oral Biosci Volume: 53(4) Pages: 289-297
  • NAID: 10030175500
  • Peer Reviewed
• [Journal Article] Peripheral and Central Mechanisms of Trigeminal Neuropathic and Inflammatory Pain (2011)
  • Author(s): Takeda M
  • Journal Title: J.Oral Biosci. Volume: 53 Pages: 289-297
  • Peer Reviewed
• [Presentation] Heat hyperalgesia in mice model of burning mouth syndrome (2011)
  • Author(s): Shinoda M
  • Organizer: Society for Neuroscience 2011
  • Place of Presentation: Washington D.C.(U.S.A)
  • Year and Date: 2011-11-12
• [Presentation] Heat hyperalgesia in mice model of burning mouth syndrome (2011)
  • Author(s): Shinoda M.
  • Organizer: Society for Neuroscience 2011
  • Place of Presentation: Washington D. C. USA
• [Remarks] 日本大学歯学部生理学教室のホームページ
  • URL: http://www.dent.nihon-u.ac.jp/phisio/gs_top.html
• [Remarks]
  • URL: http://www.dent.nihon-u.ac.jp/phisio/gs_top.html