Cleft palate and filopodia the influence of inositol will prevent cleft palate-
| Project/Area Number |
22792028
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 口蓋裂 / イノシトール / 予防 / Filopodia / アクチン線維 / 口唇口蓋裂 / AJ系マウス / ICR系マウス / フィロポディア |
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| Research Abstract |
A/J mouse witch is the spontaneous CLP strain was used and the inositol medication group and the control group considered incidence of CLP. By the inositol group, the unilateral cleft lip and palate(UCLP) was not accepted at all, but a bilateral cleft lip and palate(BCLP) accepted the control tendency as compared with the control. In morphologic observation, the systemic influence on the pregnant body or an embryo was not accepted. It has an effect which controls BCLP considered that the obstacle of inositol is serious. Furthermore, it was thought that inositol was useful as a prevention method of CLP since there is nothing influence for pregnant women and embryo.
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Report
(3 results)
Research Products
(2 results)
