The chenge of emotion and stress biomarkers which malocclusion induces.

Research Project

Project/Area Number	22792031
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Orthodontic/Pediatric dentistry
Research Institution	Hokkaido University
Principal Investigator	SUGAWARA Yuki 北海道大学, 歯学研究科(研究院), 助教 (50360920)
Project Period (FY)	2010-04-01 – 2014-03-31
Project Status	Completed (Fiscal Year 2013)
Budget Amount *help	¥4,223,793 (Direct Cost: ¥3,249,072、Indirect Cost: ¥974,721) Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000) Fiscal Year 2012: ¥323,793 (Direct Cost: ¥249,072、Indirect Cost: ¥74,721) Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords	ｆMRI / 不正咬合 / BALB/c-bm/bm / マイクロCT / Functional MRI
Research Abstract	We used functional MRI to investigate brain activity in adult volunteers when they viewed mixed emotional facial expressions (happy, angry and neutral) . All examinees were subjected to complete two tasks of mandibular position (lateral shift of the mandible, centric occlusion). The results (comparison between lateral shift of the mandible and centric occlusion) were as follows.When examinees viewed happy faces, they showed deactivation in Brodmann area (BA) 3,18,11.When they viewed angry faces, there was an increased activation in BA19.These results may suggest that there are very sensitive systems in the brain for angry face by mandibular lateral shift.