The elucidation of thealveolar bone bone resorption mechanism with tooth eruption
Project/Area Number |
22792063
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Orthodontic/Pediatric dentistry
|
Research Institution | Kyushu Dental College |
Principal Investigator |
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | 歯学 / 骨吸収 / 破骨細胞 / 細胞接着 / 萌出 / 歯の萌出 / 歯槽骨骨吸収 / 歯槽骨 / イノシトール1,4,5-三リン酸受容体 / Adenophostin A |
Research Abstract |
Inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs) are Ca2+channels that localize to intracellular Ca2+stores. Our data strongly suggest IP3R type III may be related to regulation of an actin cytoskeleton in podosomes, actin-rich adhesion structures in osteoclasts and may be associated with the alveolar bone bone resorption.
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Report
(4 results)
Research Products
(6 results)