Association of genetic polymorphisms with the therapeutic effect of functional orthodontic appliance.

• Project/Area Number: 22792067
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Orthodontic/Pediatric dentistry
• Research Institution: Showa University
• Principal Investigator: TOMOYASU Yohko 昭和大学, 歯学部, 助教 (50551206)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 下顎骨 / 成長 / 歯科矯正学

Research Abstract

The aim of this study is to examine the association between single nucleotide polymorphisms(SNPs) in the growth hormone receptor gene(GHR) and the therapeutic effect of functional orthodontic appliance. In conclusion, we did not find any association between GHR polymorphisms and the therapeutic effect of orthodontic functional appliance in the Japanese population.

Research Products

• [Journal Article] Craniofacial and dental characteristics of Japanese patients with primary failure of tooth eruption (2011)
  • Author(s): Yamaguchi T, Tomoyasu Y, Shirota T, Takahashi M, Nakano H, Kurabayashi H, Shintani S, Maki K
  • Journal Title: Hosp Dent Oral-Maxillofac Surg Volume: 23(1) Pages: 11-15
  • Peer Reviewed
• [Journal Article] Craniofacial and dental characteristics of Japanese patients with primary failure of tooth eruption (2011)
  • Author(s): Ymaguchi T, Tomoyasu Y
  • Journal Title: Hosp Dent Oral-Maxillofac Surg Volume: 23 Pages: 11-15
  • Peer Reviewed
• [Book] Principles in Contemporary Orthodontics (2011)
  • Author(s): Yoko Tomoyasu
  • Total Pages: 584
  • Publisher: In Tech
• [Book] Principles in Contemporary Orthodontics.(Recent Advances in the Genetics of Orthodontics.) Chapter 25
  • Author(s): Tomoyasu Y, Yamaguchi T, Maki k
  • Publisher: InTech