Examination of pathogenesis of periodontal disease through ascorbic acid transporter SVCTs
| Project/Area Number |
22792099
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Periodontal dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
IWASAKI Kengo 東京医科歯科大学, 大学院・医歯学総合研究科, 寄附講座教員 (40401351)
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 幹細胞 / アスコルビン酸代謝 / 歯根膜 / 歯周組織 / 再生 |
|---|
| Research Abstract |
Ascorbic acid is water-soluble vitamin which has important role in collagen metabolism. This study revealed that SVCTs, ascorbic acid transporter, expressed widely in collagen-rich connective tissue, periodontal ligament. This result suggests that SVCT may contribute to keeping of homeostasis of periodontal tissues and to pathogenesis of periodontal disease.
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Report
(3 results)
Research Products
(5 results)
