| Project/Area Number |
22792176
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Clinical nursing
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| Research Institution | Kanazawa University |
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Principal Investigator |
SUGA Yukio 金沢大学, 薬学系, 助教 (00467101)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 癌化学療法 / 嗅覚障害 / 栄養状態 / 栄養障害 |
|---|
| Research Abstract |
Olfactory dysfunction, which is considered to be a cause of appetite loss, may influence nutrition status in patients receiving cancer chemotherapy. Therefore, we evaluated the current status of olfactory dysfunction induced by antitumor drugs and its relationship with the nutrition status of the patient. Olfactory dysfunction was observed in 36% patients receiving cancer chemotherapy. Body mass index and serum protein levels significantly decreased in the patients with subjective olfactory dysfunction than in those without. These results suggest that antitumor drugs are likely to cause olfactory dysfunction, which in turn affects nutrition status in patients receiving cancer chemotherapy.
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