| Budget Amount *help |
¥3,146,000 (Direct Cost: ¥2,420,000、Indirect Cost: ¥726,000)
Fiscal Year 2011: ¥1,508,000 (Direct Cost: ¥1,160,000、Indirect Cost: ¥348,000)
Fiscal Year 2010: ¥1,638,000 (Direct Cost: ¥1,260,000、Indirect Cost: ¥378,000)
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| Research Abstract |
To analyze the mechanisms of gastrointestinal cancer progression and metastasis which result in many patient death, tumor cells from mouse genetic models were used to establish a new in vitro system. Tumor cells were isolated from genetic and chemical mouse models for gastric and intestinal tumor formation, cultured and passaged. Transfection of expression vector was also possible in these cells. This system can be utilized for the identification of candidate genes which relate to cancer progression and metastasis.
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