The antitumor effects of nerve growth factor on human cancer cells
Project/Area Number |
22800045
|
Research Category |
Grant-in-Aid for Research Activity Start-up
|
Allocation Type | Single-year Grants |
Research Field |
Applied health science
|
Research Institution | Okayama University |
Principal Investigator |
TAKATORI Shingo 岡山大学, 大学院・医歯薬学総合研究科, 助教 (20368707)
|
Co-Investigator(Renkei-kenkyūsha) |
KAWASAKI Hiromu 岡山大学, 大学院・医歯薬学総合研究科, 教授 (60125151)
HASHIKAWA Narumi (HOBARA Narumi) 岡山理科大学, 理学部・臨床生命科学科, 講師 (30511159)
GODA Mitsuhiro 新潟大学, 大学院・医歯学総合研究科, 助教 (40585965)
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥3,081,000 (Direct Cost: ¥2,370,000、Indirect Cost: ¥711,000)
Fiscal Year 2011: ¥1,443,000 (Direct Cost: ¥1,110,000、Indirect Cost: ¥333,000)
Fiscal Year 2010: ¥1,638,000 (Direct Cost: ¥1,260,000、Indirect Cost: ¥378,000)
|
Keywords | 神経成長・栄養因子 / Nerve growth factor / がん新生血管 / 血管周囲神経 / 抗腫瘍効果 |
Research Abstract |
Our present study demonstrated new findings that NGF markedly suppressed the growth of hepatic tumor cell(HepG2) and fibrosarcoma cell(HT1080) via the indirect effect, probably innervation or maturation of tumor neovasculature.
|
Report
(3 results)
Research Products
(7 results)