Walking and brain hemodynamics among older adults with mild cognitive impairment

• Project/Area Number: 22800093
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Applied health science
• Research Institution: National Center for Geriatrics and Gerontology
• Principal Investigator: DOI Takehiko 独立行政法人国立長寿医療研究センター, 在宅医療・自立支援開発部, 流動研究員 (60589026)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥3,146,000 (Direct Cost: ¥2,420,000、Indirect Cost: ¥726,000); Fiscal Year 2011: ¥1,508,000 (Direct Cost: ¥1,160,000、Indirect Cost: ¥348,000); Fiscal Year 2010: ¥1,638,000 (Direct Cost: ¥1,260,000、Indirect Cost: ¥378,000)
• Keywords: 高齢者 / 軽度認知障害 / 歩行 / 脳機能

Research Abstract

The aim of study is to clarify relationship between brain activation during walking among older adults with mild cognitive impairment. Brain activation in prefrontal region was higher during dual-task walking than normal walking. Brain activation during dual-task walking correlated with executive function. We reveal dual-task walking could activate prefrontal region in brain among older adults with mild cognitive impairments.

Research Products

• [Journal Article] Brain Atrophy and Trunk tability during Dual-task Walking among Older Adults (2011)
  • Author(s): Doi T, Makizako H, Shimada H, Yoshida D, Ito K, Kato T, Ando H, Suzuki T
  • Journal Title: J Gerontol A Biol Sci Med Sci
  • Peer Reviewed
• [Journal Article] Brain atrophy and trunk stability during dual-task walking among older adults (2011)
  • Author(s): Doi T, Makizako H, Shimada H, Yoshida D, Ito K, Kato T, et al
  • Journal Title: Journal of Gerontology : Medical Sciences Volume: (印刷中) Issue: 7 Pages: 790-795
  • DOI: 10.1093/gerona/glr214
  • Peer Reviewed
• [Presentation] The characteristics of mobility and cognitive function in early and late stage with mild cognitive impairment (2011)
  • Author(s): Takehiko Doi
  • Organizer: 16th International World Physical Therapy
  • Place of Presentation: Amsterdam
  • Year and Date: 2011-06-23
• [Presentation] The characteristics of mobility and cognitive function in early and late stage with mild cognitive impairment (2011)
  • Author(s): Doi T, Shimada H, Makizako H, Yoshida D, Suzuki T
  • Organizer: 16th International World Physical Therapy
  • Place of Presentation: Amsterdam, Holland
• [Presentation] The association between toe grip strength and fear of falling among frail older people (2010)
  • Author(s): Takehiko Doi
  • Organizer: 11th International Congress of the Asian Confederation of Physical Therapy
  • Place of Presentation: Denpasar
  • Year and Date: 2010-10-11
• [Presentation] Multiple-Step-Testは転倒リスク評価は有用か? (2010)
  • Author(s): 堤本広大, 土井剛彦, など
  • Organizer: 転倒予防医学研究会「第7回研究集会」
  • Place of Presentation: 東京
  • Year and Date: 2010-10-03
• [Presentation] The association between toe grip strength and fear of falling among frail older people (2010)
  • Author(s): Doi T, Hirata S, Fukumoto T, Misu S, Tsutsumimoto K, Osawa C, Haruna M
  • Organizer: 11th International Congress of the Asian Confederation of Physical Therapy
  • Place of Presentation: Denpasar, Indonesia
• [Presentation] Multiple-Step-Testは転倒リスク評価に有用か (2010)
  • Author(s): 堤本広大,土井剛彦,三栖翔吾,平田総一郎
  • Organizer: 転倒予防医学研究会「第7回研究集会」
  • Place of Presentation: 東京