| Budget Amount *help |
¥3,146,000 (Direct Cost: ¥2,420,000、Indirect Cost: ¥726,000)
Fiscal Year 2011: ¥1,508,000 (Direct Cost: ¥1,160,000、Indirect Cost: ¥348,000)
Fiscal Year 2010: ¥1,638,000 (Direct Cost: ¥1,260,000、Indirect Cost: ¥378,000)
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| Research Abstract |
To analyze the regulatory mechanism of patterned deposition of secondary cell walls in xylem vessels, I focused on the function of MIDD1, which interacts with both plasma membrane and cortical microtubules. I found that ROP GTPase is locally activated to recruit MIDD1 at the plasma membrane, which results in disassembly of cortical microtubules for formation of secondary cell wall pits. I also found that a mutual inhibitory interaction between ROP GTPase and cortical microtubules via MIDD1 induces the distinct pattern of secondary cell walls.
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