| Project/Area Number |
22890077
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
|
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| Research Institution | Shinshu University |
|---|
Principal Investigator |
TSUKADA Keita 信州大学, 医学部・附属病院, 助教 (90419375)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
YANO Takuya 信州大学, 医学部・附属病院, 医員 (10511058)
NISHIO Shin-ya 信州大学, 医学部, 助教 (70467166)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,068,000 (Direct Cost: ¥2,360,000、Indirect Cost: ¥708,000)
Fiscal Year 2011: ¥1,469,000 (Direct Cost: ¥1,130,000、Indirect Cost: ¥339,000)
Fiscal Year 2010: ¥1,599,000 (Direct Cost: ¥1,230,000、Indirect Cost: ¥369,000)
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| Keywords | 老人性難聴 / ミトコンドリア / 内耳 / 多型 / 遺伝子 |
|---|
| Research Abstract |
The age related hearing impairment is one of the most important problems of the aging society. To investigate the age related hearing impairment, we paid attention to mitochondrial DNA SNPs that thought to be related to aging. We performed systemic mutational analysis of mtDNA in 384 Japanese patients with hearing loss, and detected 2 novel pathogenic mitochondrial variants.
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