| Project/Area Number |
22890101
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Immunology
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
HIRAYASU Kouyuki Osaka University, 免疫学フロンティア研究センター, 特任研究員(常勤) (30585170)
|
|---|
| Project Period (FY) |
2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥1,638,000 (Direct Cost: ¥1,260,000、Indirect Cost: ¥378,000)
Fiscal Year 2010: ¥1,638,000 (Direct Cost: ¥1,260,000、Indirect Cost: ¥378,000)
|
|---|
| Keywords | KIR / 感染症 / NK細胞 / 病原体 |
|---|
| Research Abstract |
Killer immunoglobulin-like receptors (KIRs) have been shown to play a crucial role in regulating the activation of NK cells. To find out the novel ligand for KIRs, KIR-Ig fusion proteins were produced in this study. The binding of KIR2DS4-Ig to specific virus infected cells was detected, indicating that specific virus infected cells expressed unknown ligand for KIR2DS4.
|
