Research of the new target for the treatment of disorders of nerves
| Project/Area Number |
22890107
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Osaka University |
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Principal Investigator |
OKADA Kiyoshi 大阪大学, 医学部附属病院, 医員 (40576279)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,068,000 (Direct Cost: ¥2,360,000、Indirect Cost: ¥708,000)
Fiscal Year 2011: ¥1,469,000 (Direct Cost: ¥1,130,000、Indirect Cost: ¥339,000)
Fiscal Year 2010: ¥1,599,000 (Direct Cost: ¥1,230,000、Indirect Cost: ¥369,000)
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| Keywords | 脊髄損傷 / 末梢神経 / 再生 / Icmt / 小脳顆粒細胞 / mTOR |
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| Research Abstract |
In this research, we found that the Akt/ mTOR signaling pathway related with Icmtcontrols neurite outgrowth and neuronal apoptosis. We believe that Icmt has apotential to become a new target to treat several nervous disorders, and furtherinvestigation of the effects of Icmt may reveal new insights into nerveregeneration and the treatment of several nervous diseases and injuries.
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Report
(3 results)
Research Products
(16 results)
