• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The Regenerative Medicine in Mandibular Condylar Chondrocytes by The Application of Control Technology of Low-intensity Pulsed Ultrasound on the Matrix Metabolism

Research Project

Project/Area Number 22890122
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Orthodontic/Pediatric dentistry
Research InstitutionHiroshima University

Principal Investigator

IWABUCHI Yasunori  広島大学, 病院, 歯科診療医 (30580906)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥2,405,000 (Direct Cost: ¥1,850,000、Indirect Cost: ¥555,000)
Fiscal Year 2011: ¥949,000 (Direct Cost: ¥730,000、Indirect Cost: ¥219,000)
Fiscal Year 2010: ¥1,456,000 (Direct Cost: ¥1,120,000、Indirect Cost: ¥336,000)
Keywords歯学 / 細胞・組織 / シグナル伝達 / 移植・再生医療 / 再生医学
Research Abstract

Stimulation over the opening cartilage for temporomandibular joint in rats, promote the secretion of IL-1βin the mesenchymal layer of cartilage, reduced the proteoglycan of hyaline cartilage layer of the surface cartilage and hyaluronic acid. By irradiation of a rat model of LIPUS for the opening over, a decrease in IL-1βcompared to the non-irradiated group, the increase in proteoglycan On the other hand was observed. Suppressor pathway for IL-1βof LIPUS, LIPUS pathways inhibited the enhancement of COX-2 and ERK-1/ 2 by activating integrin under inflammation, called to suppress the IL-1βhas been suggested.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (1 results)

All 2010

All Presentation (1 results)

  • [Presentation] 退行性変性を呈する下顎頭軟骨に対する低出力超音波(LIPUS)照射の影響について2010

    • Author(s)
      岩渕泰憲
    • Organizer
      第69回日本矯正歯科学会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-28
    • Related Report
      2011 Final Research Report 2010 Annual Research Report

URL: 

Published: 2010-08-27   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi