Investigation of the transmission mechanism of RSV among Vietnamese children

• Project/Area Number: 22890137
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Public health/Health science
• Research Institution: Nagasaki University
• Principal Investigator: SUZUKI Motoi 長崎大学, 熱帯医学研究所, 助教 (60444874)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥3,146,000 (Direct Cost: ¥2,420,000、Indirect Cost: ¥726,000); Fiscal Year 2011: ¥1,508,000 (Direct Cost: ¥1,160,000、Indirect Cost: ¥348,000); Fiscal Year 2010: ¥1,638,000 (Direct Cost: ¥1,260,000、Indirect Cost: ¥378,000)
• Keywords: RSウイルス / ベトナム / 国際情報交換 / RSV感染症 / 細気管支炎 / 感染症疫学

Research Abstract

We investigated the effect of respiratory viruses single and multiple infections on risk of lower respiratory tract infections (LRTIs) in Vietnam. Nasopharyngeal samples were collected from 1,992 hospitalized children with acute respiratory infections and tested for 13 respiratory viruses. 60.9% were positive for at least one virus, and 9.5% had multiple-viral infections. RSV and human metapneumovirus (HMPV) infections independently increased the risk of LRIs. RSV further increased the risk, when co-infected with HRVand HMPV.

Research Products

• [Journal Article] Respiratory syncytial virus, its co-infection and paediatric lower respiratory infections (2013)
  • Author(s): Yoshida LM, Suzuki M, Nguyen HA, Le MN, Vu TD, Yoshino H, Schmidt WP, Nguyen TT, Tho Le H, Morimoto K, Moriuchi H, Dang DA, Ariyoshi K
  • Journal Title: Eur Respir J
  • Peer Reviewed
• [Journal Article] Does Respiratory Virus Coinfection Increases the Clinical Severity of Acute Respiratory Infection Among Children Infected With Respiratory Syncytial Virus? (2013)
  • Author(s): Harada Y, Kinoshita F, Yoshida L, Minh LN, Suzuki M, Morimoto K, Toku Y, Tomimasu K, Moriuchi H, Ariyoshi K
  • Journal Title: Pediatric Infectious Disease Journal Volume: 32(5)
  • Peer Reviewed
• [Journal Article] Respiratory syncytial virus, its co-infection and paediatric lower respiratory infections. (2013)
  • Author(s): Yoshida Laymyint and Motoi Suzuki (equally contribution)
  • Journal Title: European Respiratory Journal Volume: online
  • Peer Reviewed
• [Journal Article] Incidence of Radiologically Confirmed Pneumonia and Haemophilus influenzae type b Carriage before Hib Vaccine Introduction in Central Vietnam
  • Author(s): Lay-Myint Yoshida, Hien-Anh Nguyen, Kiwao Watanabe, Minh Nhat Le, Ai Thi Thuy Nguyen, Huong Thi Thu Vu, Hiroshi Yoshino, Motoi Suzuki, Kensuke Takahashi, Tho Huu Le, Paul E. Kilgore, Karen Edmond, Kim Mulholland, Duc-Anh Dang, Koya Ariyoshi
  • Journal Title: Journal of Infection
  • Peer Reviewed