Analysis of physi ological function for new peptides derived from VGF protein discovered by peptidomics analysis
| Project/Area Number |
22890253
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Endocrinology
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| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
MOCHIZUKI Akikazu 独立行政法人国立循環器病研究センター, 分子薬理部, 研究員 (30589601)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,068,000 (Direct Cost: ¥2,360,000、Indirect Cost: ¥708,000)
Fiscal Year 2011: ¥1,469,000 (Direct Cost: ¥1,130,000、Indirect Cost: ¥339,000)
Fiscal Year 2010: ¥1,599,000 (Direct Cost: ¥1,230,000、Indirect Cost: ¥369,000)
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| Keywords | VGF / ペプチド / ノックアウトマウス / 生理活性ペプチド / ペプチドーム / 遺伝子欠損マウス |
|---|
| Research Abstract |
In this study, we found NERP-1 and NERP-2 producing cells are colocalized with CRH immunopositive cells. We made antibodies against for NERP-3 and NERP-4.In addition, we made VGF knockout mouse. They are lean and inferility.
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Report
(3 results)
Research Products
(7 results)
