Motor-based molecular machines in action: Winch & Gears
| Project/Area Number |
22H00325
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Review Section |
Medium-sized Section 34:Inorganic/coordination chemistry, analytical chemistry, and related fields
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| Research Institution | Nara Institute of Science and Technology |
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Principal Investigator |
ラッペン ゲナエル 奈良先端科学技術大学院大学, 先端科学技術研究科, 教授 (60812576)
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| Co-Investigator(Kenkyū-buntansha) |
川井 茂樹 国立研究開発法人物質・材料研究機構, マテリアル基盤研究センター, グループリーダー (30716395)
西野 智雄 奈良先端科学技術大学院大学, 先端科学技術研究科, 助教 (60824878)
安原 主馬 奈良先端科学技術大学院大学, 先端科学技術研究科, 准教授 (90545716)
服部 陽平 奈良先端科学技術大学院大学, 先端科学技術研究科, 特任助教 (30843271)
尾本 賢一郎 奈良先端科学技術大学院大学, 先端科学技術研究科, 特任助教 (40820056)
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| Project Period (FY) |
2022-04-01 – 2027-03-31
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| Project Status |
Granted (Fiscal Year 2024)
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| Budget Amount *help |
¥41,860,000 (Direct Cost: ¥32,200,000、Indirect Cost: ¥9,660,000)
Fiscal Year 2024: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Fiscal Year 2023: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
Fiscal Year 2022: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
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| Keywords | Molecular gears / Ruthenium complexes / Lanthanide complexes / Aromatic compounds / STM / Molecular machines / Double-decker complexes / Molecular gear / Single molecule / Tripodal ligand |
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| Outline of Research at the Start |
Exploitation of machines at the single molecular level is the ultimate miniaturization for the emergence of radically new technologies in the field of nanomedicine, sustainable development and energy harvesting. Molecular design, chemical synthesis and STM experiments will be combined to investigate the mechanical properties of rotating molecular machines. Our goal is to push molecular machines from the flask to the real world with prototypes of winches and gears. Transfer of rotation in a train of gears will be achieved and the laws governing the mechanics of such movements established.
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| Outline of Annual Research Achievements |
In this first year, a new series of molecular gears have been synthesized. They are ruthenium-based molecular gear prototypes composed of a brominated or non-brominated pentaphenylcyclopentadienyl ligand as an anchoring unit and a tripodal ligand with aryl-functionalized indazoles as a rotating cogwheel. The appended aryl groups increase the apparent diameter of the cogwheel rendering them larger than the diameter of the anchoring units and consequently making them suitable for intermolecular gearing motions once the complexes will be adsorbed on a surface. The STM studies have been started but are not conclusive yet.
The nano-winch has also all been successfully synthesized with a family of loads of a wide variety exhibiting very different structures from fullerenes, triptycenes, and porphyrins.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
The research is going smoothly as expected. For this second year, more manpower is required to explore the different designs we proposed in the project. We plan to enroll a new specially appointed assistant professor on the project after a former one left this month. A collaboration with a theoretician (Dr. J. Cuny from the University of Toulouse, France) has been established to modelize the intermolecular interactions in a train of molecular gears to evaluate the energy barrier of such transfer of rotation as well as to determine the best teeth structures of the cogwheels.
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| Strategy for Future Research Activity |
We plan to start the synthesis of a new series of molecular gears with more teeth by using cyclooctatetraene-based cogwheels. In parallel, the deposition of the new series (4 different molecular gears) and the nano-winch obtained during the first year will be done on different metal surfaces and their manipulation using the tip of a scanning tunneling microscope (STM) will be explored with the goal to follow the transfer of rotation from one molecule to the next.
The molecular gears will be studied in the group of Dr. Shigeki Kawai (NIMS, Tsukuba) whereas the nanowinch will be sent to Prof. Saw-Wai Hla (Ohio University, USA) who has already the knowledge of these ruthenium double-decker complexes.
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Report
(2 results)
Research Products
(3 results)
