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Discovery of novel cancer treatment through elucidation of cGAS/STING pathway in lung squamous cell carcinoma

Research Project

Project/Area Number 22K08289
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 53030:Respiratory medicine-related
Research InstitutionKeio University

Principal Investigator

寺井 秀樹  慶應義塾大学, 医学部(信濃町), 講師 (50445293)

Project Period (FY) 2022-04-01 – 2025-03-31
Project Status Granted (Fiscal Year 2022)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2024: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2023: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2022: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
KeywordsSTING / 肺扁平上皮癌 / ICI
Outline of Research at the Start

肺扁平上皮癌患者における免疫チェックポイント阻害剤有効性に関わる腫瘍細胞の性質と自然免疫経路との関わりについて調査を行う。
本研究により、免疫チェックポイント阻害剤有効性のバイオマーカーや抵抗性克服のための新たな治療標的を見出すことを目的とする。

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Published: 2022-04-19   Modified: 2022-07-01  

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