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CFD simulations guided prevention and mitigation of Airborne Disease Transmission

Research Project

Project/Area Number 22K10596
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
Research InstitutionInstitute of Physical and Chemical Research

Principal Investigator

BALE RAHUL  国立研究開発法人理化学研究所, 計算科学研究センター, 研究員 (20728737)

Project Period (FY) 2022-04-01 – 2025-03-31
Project Status Granted (Fiscal Year 2023)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2024: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2023: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2022: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
KeywordsDroplet modelling / Indoor ventilation / Droplet modeling / Airborne Disease / Droplet Dispersion / Epidemiology
Outline of Research at the Start

The COVID-19 pandemic has shown the devastation that airborne diseases can cause. Globally, COVID-19 has claimed over 4.5M lives (16000 in Japan). The impact on the Japanese economy has been equally severe. To control and prevent such future pandemics, understanding the detailed mechanism of airborne disease transmission (ADT) is critical. Recent and past research studies involving real-world conditions are very few and limited in scope. The reason for this is the limitation in the CFD tool’s capability. In this work, we propose to develop CFD methods capable of overcoming past limitations.

Outline of Annual Research Achievements

Modeling the various time scales involved in droplet emission and translation is one of the key challenges that was to be addressed in this work. We have successfully incorporated implicit schemes for species and N-S equations and a sub-time-stepping approach for the droplet dynamics to enable long-time droplet dispersion dynamics.

In addition to this we have already been able to apply the models developed so far to various applications ranging from indoor ventilation efficacy evaluation, multi-objective ventilation optimization, inhalation and deposition mechanism using detailed respiratory tract and realistic breathing cycle. The investigation of the deposition of respiratory droplets in respiratory tract involved interaction between two human subjects, one emitting droplet which modelled human speech, and the other subject inhaling with a detailed respiratory tract. The role of distance between the subjects, the orientation of the face along sideways and un-down were investigated in this study. Furthermore, the necessity of the a respiratory tract based inhalation for infection risk assessment as opposed to evaluating the risk based on the droplets entering the breathing zone was also investigated in the study.

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

The project has progressed as planned except for the development of the droplet model to mimic the sputum liquid instead of the simple water.

Strategy for Future Research Activity

The next phase of the project will involve development of a droplet model that can mimic the evaporation of the sputum fluid, development of generalized real world setting that incorporates, droplet emission, transport, interaction with obstacles, and inhalation, evaluation of the role of environmental factors on the transmission of airborne pathogens.

Report

(2 results)
  • 2023 Research-status Report
  • 2022 Research-status Report
  • Research Products

    (3 results)

All 2024 2023

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results)

  • [Journal Article] Droplet dispersion simulation to evaluate airborne virus infection risk in outdoor sports stadiums2024

    • Author(s)
      KIM Sangwon、ONISHI Junya、BALE Rahul、TSUBOKURA Makoto
    • Journal Title

      Journal of Fluid Science and Technology

      Volume: 19 Issue: 2 Pages: JFST0008-JFST0008

    • DOI

      10.1299/jfst.2024jfst0008

    • ISSN
      1880-5558
    • Related Report
      2023 Research-status Report
  • [Journal Article] Large eddy simulation of droplet transport and deposition in the human respiratory tract to evaluate inhalation risk2023

    • Author(s)
      Murga Alicia、Bale Rahul、Li Chung-Gang、Ito Kazuhide、Tsubokura Makoto
    • Journal Title

      PLOS Computational Biology

      Volume: 19 Issue: 3 Pages: 1-21

    • DOI

      10.1371/journal.pcbi.1010972

    • Related Report
      2023 Research-status Report 2022 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Characterizing infection risk in a restaurant environment due to airborne diseases using discrete droplet dispersion simulations2023

    • Author(s)
      Bale Rahul、Li ChungGang、Fukudome Hajime、Yumino Saori、Iida Akiyoshi、Tsubokura Makoto
    • Journal Title

      Heliyon

      Volume: 9 Issue: 10 Pages: e20540-e20540

    • DOI

      10.1016/j.heliyon.2023.e20540

    • Related Report
      2023 Research-status Report

URL: 

Published: 2022-04-19   Modified: 2024-12-25  

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