| Project/Area Number |
22K13677
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 09030:Childhood and nursery/pre-school education-related
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| Research Institution | University of Fukui |
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Principal Investigator |
Natasha Kawata 福井大学, 子どものこころの発達研究センター, 特命助教 (70923415)
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| Project Period (FY) |
2022-04-01 – 2024-03-31
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| Project Status |
Granted (Fiscal Year 2022)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2023: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2022: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Keywords | Child maltreatment / auditory / MRI / VBM / rs-fMRI / DTI / Maltreatment children / auditory ability / children abuse / trauma |
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| Outline of Research at the Start |
This study examines the relationship between auditory measure and social scale, GMV, and functional connectivity in children with PVA experiences. All participants will be scanned using a 3-Tesla MR scanner with a 32-channel head coil. High-resolution structural whole-brain images will be acquired using a 3D T1-weighted fast spoiled gradient-recalled imaging sequence. All participants will undergo DTI and rs-fMRI measurements.To assess auditory abilities, participants will undergo an auditory threshold.
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| Outline of Annual Research Achievements |
During the current academic year, a dataset comprising information from 60 children was utilized. In addition to demographic data, we collected magnetic resonance imaging (MRI) and hearing data. To be more specific, we performed MRI scans on all 60 subjects using three protocols: T1 imaging for brain structure analysis, resting state functional MRI (fMRI) for examining functional connectivity, and diffusion imaging for investigating brain structure.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
This research will utilize magnetic resonance data obtained from a sample of 60 individuals to conduct both structural and functional analyses. The primary goal is to investigate the impact of environmental factors on brain development related to hearing.
Originally, data acquisition for MRI scans and hearing thresholds of the 60 subjects was scheduled for the current fiscal year. However, the sample collection was completed earlier than anticipated. We are currently assessing the quality of the images and verifying the inclusion criteria for subjects with typical development, before commencing with the data analysis.
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| Strategy for Future Research Activity |
Over the upcoming academic years, all data collected - including data from the cognitive and auditory questionnaire - will be consolidated into a unified table. Furthermore, collaborative efforts with the University of Western's laboratories will commence for the analysis of magnetic resonance data.
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