| Project/Area Number |
22K13677
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 09030:Childhood and nursery/pre-school education-related
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| Research Institution | University of Fukui |
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Principal Investigator |
Natasha Kawata 福井大学, 子どものこころの発達研究センター, 特命助教 (70923415)
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| Project Period (FY) |
2022-04-01 – 2025-03-31
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| Project Status |
Granted (Fiscal Year 2023)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2023: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2022: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Keywords | Child maltreatment / auditory / MRI / VBM / rs-fMRI / DTI / Maltreatment children / auditory ability / children abuse / trauma |
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| Outline of Research at the Start |
This study examines the relationship between auditory measure and social scale, GMV, and functional connectivity in children with PVA experiences. All participants will be scanned using a 3-Tesla MR scanner with a 32-channel head coil. High-resolution structural whole-brain images will be acquired using a 3D T1-weighted fast spoiled gradient-recalled imaging sequence. All participants will undergo DTI and rs-fMRI measurements.To assess auditory abilities, participants will undergo an auditory threshold.
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| Outline of Annual Research Achievements |
The collected data were converted from DICOM to NIfTI format for the three modalities: T1, DTI, and Rest. Data quality checks were performed on 120 subjects. Pre-processing of the DTI modality was completed for 114 subjects.
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| Current Status of Research Progress |
Current Status of Research Progress
3: Progress in research has been slightly delayed.
Reason
Magnetic resonance data were obtained from other study protocols. To verify the exclusion criteria, it was necessary to locate the subjects' data and gather information from other assessments.
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| Strategy for Future Research Activity |
The analysis will be conducted across three modalities. First, the T1 modality will be examined. Once the MRI results are established, they will be compared with behavioral assessments. Next, the resting-state images will be analyzed to verify the correlation between structural alterations and functional changes. Finally, DTI images will be analyzed to complement our findings.
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