Interaction of non-Newtonian fluids with deformable structures in microscale biological processes
| Project/Area Number |
22K14184
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 19010:Fluid engineering-related
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| Research Institution | Okinawa Institute of Science and Technology Graduate University |
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Principal Investigator |
VARCHANIS Stylianos 沖縄科学技術大学院大学, マイクロ・バイオ・ナノ流体ユニット, ポストドクトラルスカラー (30913462)
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| Project Period (FY) |
2022-04-01 – 2024-03-31
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| Project Status |
Granted (Fiscal Year 2022)
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| Budget Amount *help |
¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2023: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2022: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | Viscoelastic / FSI / Flow instability / Porous media / Microfluidics |
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| Outline of Research at the Start |
In this project, the applicant will develop a new, fully consistent, and highly stable Finite Element formulation for the simulation of the flow and interaction of viscoelastic fluids with elastic structures. This will be the first numerical method that will address the multiphysics coupling between the laws that describe non-Newtonian fluid dynamics and structural mechanics. The algorithm will be employed to study the underlying physics in a problem that arises in microscale biological processes: the 3-dimensional viscoelastic flow past a single or an array of deformable elastic posts.
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| Outline of Annual Research Achievements |
In FY2022, we developed the tools and laid the foundations for making the key in-silico experiments. Initially, we developed the algorithm and implemented it in the in-house parallel FE code. We performed strict mesh and time-step refinement convergence tests for VFSI past a single deformable cylinder. We found that the method exhibits second-order accuracy in space and time. We also validated the numerical results with microfluidic experiments of viscoelastic flow past two cantilevered cylinders; semi-quantitative agreement was achieved. All the results are summarized in a manuscript that will be submitted in the journal "Computer Methods in Applied Mechanics and Engineering".
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| Current Status of Research Progress |
Current Status of Research Progress
1: Research has progressed more than it was originally planned.
Reason
The project has progressed very well through FY2022. As initially expected, the numerical algorithm has been developed and validated. There is sufficient time in
FY2023 to carry out the bulk of the detailed simulations and elucidate the underlying physics of the process. The rather quick progress was mainly due to the large amount of preliminary research conducted prior to the beginning of the project. Additionally, the Scientific Computing and Data Analysis section of Research Support Division at OIST provided valuable help regarding coding and implementation of the algorithm.
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| Strategy for Future Research Activity |
We accomplished the planned objectives for FY2022. In FY2023, we will carry out the bulk of the detailed simulations. We will start with simulation of the base (reference) case for increasing flow rates. Then we will proceed to a wide parametric analysis the rheological properties of the viscoelastic fluid and the solid, followed by a parametric analysis regarding the geometrical properties of the physical domain. Finally, we will carry out a detailed data analysis and derive scaling relationships to relate the properties of the fluid, the solid, and the geometry with the macroscopically observed quantities (e.g., apparent permeability, slip length, frequency of oscillations). The results will be summarized in two papers. One for flow past a single deformable cylinder in a straight channel and a second one for flow past a periodic array of deformable cylinders.
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Report
(1 results)
Research Products
(4 results)
