Identification of repetitive elements involving genome regulation
| Project/Area Number |
22K15093
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 43060:System genome science-related
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| Research Institution | Waseda University |
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Principal Investigator |
曽 超 早稲田大学, 理工学術院総合研究所(理工学研究所), 次席研究員(研究院講師) (80822460)
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| Project Period (FY) |
2022-04-01 – 2025-03-31
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| Project Status |
Granted (Fiscal Year 2022)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2024: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2023: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2022: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | R-loop / repetitive element / TF / chromatin |
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| Outline of Research at the Start |
DNA-RNA hybrid (R-loop) and DNA-protein association are both molecular interactions that influence chromatin dynamics and genome regulation. The purpose of this study is to identify repetitive elements regulating DNA-RNA/protein association from public R-loop sequencing data and ChIP-seq data.
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| Outline of Annual Research Achievements |
今年度、数十の生物種から約2,000個のR-loopのシーケンシングデータセットを収集し、一部のデータセットのリードマッピングとピークコーリング解析を完了しました。
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
R-loopのシーケンシングデータの解析パイプラインを作成し、約600個のデータを解析できた。
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| Strategy for Future Research Activity |
今年度の解析結果をR-loopデータベースに統合した上、リピートエレメントとR-loop形成の関連を解析します。
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Report
(1 results)
Research Products
(1 results)
