| Project/Area Number |
22K15800
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 52040:Radiological sciences-related
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| Research Institution | Gunma University |
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Principal Investigator |
K AchmadA.P. 群馬大学, 大学院医学系研究科, 助教 (70806439)
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| Project Period (FY) |
2022-04-01 – 2024-03-31
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| Project Status |
Granted (Fiscal Year 2022)
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| Budget Amount *help |
¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2023: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2022: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | GBCA / Neutrophil elastase / alpha-1-antitrypsin / Gd deposition disease |
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| Outline of Research at the Start |
The ultimate purpose of this study is to provide relevant scientific findings regarding the toxicity of Gd so that we can take a preventive measurement to avoid further problems. Studies have revealed that hospital effluent may be the major source of anthropogenic Gd in aquatic systems. Positive Gd anomalies of variable size have been observed worldwide. Previous reports in small animal indicated that the increasing Gd concentration in the environment may be potentially toxic. Therefore, the risk of Gd deposition may not only be from clinical use.
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