| Project/Area Number |
22K16780
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 56020:Orthopedics-related
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| Research Institution | Aichi Medical University |
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Principal Investigator |
単 西瑶 愛知医科大学, 医学部, 助教 (60916625)
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| Project Period (FY) |
2022-04-01 – 2025-03-31
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| Project Status |
Granted (Fiscal Year 2022)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2024: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2023: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2022: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | Hamstrings / Aponeurosis / Stiffness / Strain-injury / Tissue mechanics / Cadaveric study / aponeurosis / muscle strain / cadaveric study / morphology / stiffness |
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| Outline of Research at the Start |
The mechanism of how aponeurosis influences muscle strain remains obscure. Thereby this research will provide insight into the contribution of aponeurosis to preventing muscle strain by understanding the structural and mechanical features of aponeurosis from strain injury-prone muscle-tendon units.
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| Outline of Annual Research Achievements |
By dissecting formalin-fixed cadavers, the mechanical and morphological properties of the hamstrings muscles and aponeuroses have been investigated.
1. Differential effects of formalin fixation on cadaveric muscles and aponeuroses were investigated;
2. Reliability and validity of the myotonometer in cadaveric studies were examined;
3. Morphological distribution characteristics of hamstrings aponeuroses were measured.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
The morphology and mechanical properties of the aponeuroses of the hamstrings has been conducted smoothly, and the samples and data were collected according to the schedule of cadaveric research at Aichi Medical University.
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| Strategy for Future Research Activity |
The morphological and mechanical properties of the aponeuroses of the quadriceps muscle will be further studied. In addition, the fiber orientation of the aponeurosis tissue will be further investigated to find the relationship between the aponeurosis and the susceptibility to strain-injury.
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