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Cadaveric investigation of the morphological and mechanical characteristics of aponeurosis on the mechanism of muscle strain injury

Research Project

Project/Area Number 22K16780
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 56020:Orthopedics-related
Research InstitutionAichi Medical University

Principal Investigator

単 西瑶  愛知医科大学, 医学部, 助教 (60916625)

Project Period (FY) 2022-04-01 – 2025-03-31
Project Status Granted (Fiscal Year 2023)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2024: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2023: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2022: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
KeywordsAponeurosis / Stiffness / Strain-injury / Tissue mechanics / Cadaveric study / MyotonPRO / Hamstring / Hamstrings / aponeurosis / muscle strain / cadaveric study / morphology / stiffness
Outline of Research at the Start

The mechanism of how aponeurosis influences muscle strain remains obscure. Thereby this research will provide insight into the contribution of aponeurosis to preventing muscle strain by understanding the structural and mechanical features of aponeurosis from strain injury-prone muscle-tendon units.

Outline of Annual Research Achievements

By dissecting formalin-fixed cadavers, the mechanical and morphological properties of the hamstring muscles and aponeuroses have been investigated.
1. Differential effects of formalin fixation on cadaveric muscles and aponeuroses were investigated;
2. Reliability and validity of the myotonometer in cadaveric studies were examined;
3. Morphological distribution characteristics of hamstrings aponeuroses were measured using the myotonometer;
4. The mechanical and morphological properties of semitendinosus were measured.

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

The morphology and mechanical properties of the aponeuroses of the hamstrings have been conducted smoothly, and the samples and data were collected according to the schedule of cadaveric research at Aichi Medical University

Strategy for Future Research Activity

The morphological and mechanical properties of the aponeuroses of the quadriceps muscle will be further studied. In addition, the fiber orientation of the aponeurosis tissue will be further investigated to find the relationship between the aponeurosis and the susceptibility to strain-injury.

Report

(2 results)
  • 2023 Research-status Report
  • 2022 Research-status Report
  • Research Products

    (5 results)

All 2024 2023

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] Assessing site-specificity of the biomechanical properties of hamstring aponeuroses using MyotonPRO: A cadaveric study2024

    • Author(s)
      Shan Xiyao、Otsuka Shun、Okubo Tomohito、Takeuchi Takao、Fukushige Kaori、Naito Munekazu
    • Journal Title

      Clinical Biomechanics

      Volume: 114 Pages: 106230-106230

    • DOI

      10.1016/j.clinbiomech.2024.106230

    • Related Report
      2023 Research-status Report
    • Peer Reviewed
  • [Journal Article] Biomechanical assessment of gastrocnemii and Achilles tendon using MyotonPRO: <i>in vivo</i> measurements, and preliminary <i>in situ</i> measurements using formalin-fixed tissues2023

    • Author(s)
      Shan Xiyao、Umemoto Kanae、Ishikawa Takuro、Fukushige Kaori、Takeuchi Takao、Naito Munekazu
    • Journal Title

      Connective Tissue Research

      Volume: 65 Issue: 1 Pages: 16-25

    • DOI

      10.1080/03008207.2023.2267682

    • Related Report
      2023 Research-status Report
    • Peer Reviewed
  • [Presentation] Is MyotonPRO a valid and reliable device for assessing mechanical properties of gastronemii and Achilles tendon in vivo and in situ2024

    • Author(s)
      Shan X., Umemoto K., Ishikawa T., Fukushige K., Takeuchi T., Naito M.
    • Organizer
      The 129th Annual Meeting of The Japanese Association of Anatomists
    • Related Report
      2023 Research-status Report
  • [Presentation] 下腿前方区画における深筋膜の形態および機械的特性2024

    • Author(s)
      木全健太郎,単西瑶,大塚俊,内藤宗和
    • Organizer
      第129回日本解剖学会総会・全国学術集会
    • Related Report
      2023 Research-status Report
  • [Presentation] 膝内側側副靱帯の形態学的および力学的特性:内側側副靱帯損傷のさらなる理解への一助2024

    • Author(s)
      梶浦大輝,齋藤壮人,梅本佳納榮,単西瑶,内藤宗和
    • Organizer
      第129回日本解剖学会総会・全国学術集会
    • Related Report
      2023 Research-status Report

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Published: 2022-04-19   Modified: 2024-12-25  

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