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Investigation of relationships between carcass traits and the rumen microbiome in Japanese Black cattle using multi-omics analysis.

Research Project

Project/Area Number 22K20608
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeMulti-year Fund
Review Section 0605:Veterinary medical science, animal science, and related fields
Research InstitutionUtsunomiya University

Principal Investigator

Sato Yoshiaki  宇都宮大学, 農学部, 助教 (10962805)

Project Period (FY) 2022-08-31 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2023: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2022: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords反芻動物 / 枝肉形質 / ルーメン微生物 / メタゲノム
Outline of Research at the Start

わが国の黒毛和種は他の外国種と比べて産肉能力に優れ、特に脂肪交雑は世界で類のないものである。海外品種において脂肪交雑とルーメン微生物が関連していることは解明されているが、黒毛和種においては明らかになっていない。本研究ではマルチオミクス解析(メタゲノム解析:細菌叢およびウイルス叢、メタボローム解析:代謝産物)を用いて黒毛和種のルーメン微生物およびその代謝産物と枝肉形質に関連があるのではないかという仮説を検証する。

Outline of Final Research Achievements

This study aimed to investigate the relationship between the rumen microbiome and carcass traits, such as marbling and carcass weight, in Japanese Black cattle. Metagenomic sequencing was used to compare the rumen microbiome between high-carcass weight (HW) and low-carcass weight (LW) cattle, and high-marbling (HM) and low-marbling (LM) cattle. As a result, the prokaryotic and viral communities in the rumens of HW vs. LW and HM vs. LM were different. In summary, this study revealed that the rumen microbiome of Japanese Black cattle was associated with carcass traits.

Academic Significance and Societal Importance of the Research Achievements

本研究の結果、黒毛和種のルーメン微生物叢と枝肉形質(脂肪交雑および枝肉重量)との間には深い関係があることが示唆された。また、脂肪交雑が高い個体や枝肉重量の大きい個体に特徴的なMetagenome-assembled genomes(MAG)が数多く見つかった。このMAGをバイオマーカーとして育種を行うことができれば、黒毛和種の枝肉形質を向上させることができ、日本の肉牛生産にも大きく貢献することができると考えられる。

Report

(3 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • Research Products

    (1 results)

All 2024

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results)

  • [Journal Article] Impact of rumen microbiome on cattle carcass traits2024

    • Author(s)
      Yoshiaki Sato, Ruki Sato, Emiko Fukui & Fumiaki Yoshizawa
    • Journal Title

      Scientific Reports

      Volume: 14 Issue: 1 Pages: 6064-6064

    • DOI

      10.1038/s41598-024-56603-3

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access

URL: 

Published: 2022-09-01   Modified: 2025-01-30  

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