Investigation and biosensing application of novel switching function in conductive polymer hydrogels
| Project/Area Number |
22KF0095
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| Project/Area Number (Other) |
22F22729 (2022)
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| Research Category |
Grant-in-Aid for JSPS Fellows
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| Allocation Type | Multi-year Fund (2023)
Single-year Grants (2022) |
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| Section | 外国 |
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| Review Section |
Basic Section 28040:Nanobioscience-related
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| Research Institution | The University of Tokyo |
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Principal Investigator |
坂田 利弥 東京大学, 大学院工学系研究科(工学部), 准教授 (70399400)
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| Co-Investigator(Kenkyū-buntansha) |
TSENG ALEX 東京大学, 大学院工学系研究科(工学部), 外国人特別研究員
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| Project Period (FY) |
2023-03-08 – 2024-03-31
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| Project Status |
Completed (Fiscal Year 2023)
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| Budget Amount *help |
¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2023: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2022: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Keywords | 導電性ポリマー / 複合体ハイドロゲル / 有機電気化学トランジスタ / electrochemical sensing / PEDOT |
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| Outline of Research at the Start |
Composite hydrogels of conductive PEDOT:PSS and modified polyacrylamides (PAAm) are promising materials for soft bioelectronics. This is because the semiconductivity of PEDOT can be preserved while designing structural and smart functions via rational selection of monomers. Therefore, we will investigate monomer compositions that optimize and combine conductance switching with chemical binding of biomolecules for sensing application in this research.
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| Outline of Annual Research Achievements |
Composite hydrogels of PEDOT:PSS and engineered acrylamide co-polymers are promising materials for soft bioelectronics. In this work, we set out to investigate the effect of monomer composition on the electrical conductance switching of PEDOT-based transistor devices and their potential for biosensing applications.
In FY2022, we achieved our main goal of incorporating UV-Vis-NIR spectroelectrochemistry into the study of these composite devices.
In FY2023, we achieved our goal of introducing additional functional monomers into the acrylamide co-polymer, in addition to the redox-active monomers. As a result, the oxidation potential of the dye molecule was lowered and this allowed for dye-protein binding interactions to be probed within the electrochemical stability window of PEDOT.
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Report
(2 results)
Research Products
(7 results)
