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Restoration of self body control by implantable FES and BMI

Research Project

Project/Area Number 22KF0236
Project/Area Number (Other) 21F21781 (2021-2022)
Research Category

Grant-in-Aid for JSPS Fellows

Allocation TypeMulti-year Fund (2023)
Single-year Grants (2021-2022)
Section外国
Review Section Basic Section 90110:Biomedical engineering-related
Research InstitutionOsaka University

Principal Investigator

平田 雅之  大阪大学, 大学院医学系研究科, 特任教授(常勤) (30372626)

Co-Investigator(Kenkyū-buntansha) FORTUNE BENJAMIN  大阪大学, 大学院医学系研究科, 外国人特別研究員
Project Period (FY) 2023-03-08 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 2023: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2022: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2021: ¥1,200,000 (Direct Cost: ¥1,200,000)
Keywordsブレインマシンインターフェース / 機能的電気刺激 / 体内埋込み / 機能再建
Outline of Research at the Start

The optimal method for motor control in paralyzed people is to restore self-body control without using any assistive tools such
as prosthetic arms. In this study, will establish a new FES method using nerve trunk stimulation, and couple it with the existin
g implantable BMI system.

Outline of Annual Research Achievements

Animal experiments were performed to investigate the feasibility of the nerve trunk stimulation. The animal experiments focused on fine motor control using super-selective nerve trunk stimulation. Feasibility of the nerve truck stimulation was evaluated.
A bench test model of the implantable FES device was developed to evaluate the feasibility of implantable FES. A cuff-type electrode sheet and a helical-type electrode sheet were developed to stimulate on the nerve trunks of the upper and lower limbs.
Bench tests of the test model of the implantable FES device demonstrated that the model works well as specified. Animal experiments using macaque monkeys were performed regarding the upper limb and successfully demonstrated that both of the electrode sheets were able to stimulate selective contraction of the innervated muscles. Further investigation will be required to successfully evoke super-selective contraction of the single muscle of each finger
The budget related to this research project over 2022-2024 is larger than the budget of this grant, therefore, for additional assistance, a KAKENHI KIBAN A was used to cover the total budget. The budget of this grant in 2023 was used for a part of this study: expendables required for experiments.

Report

(3 results)
  • 2023 Annual Research Report
  • 2022 Annual Research Report
  • 2021 Annual Research Report
  • Research Products

    (11 results)

All 2023 2022

All Journal Article (1 results) Presentation (7 results) (of which Int'l Joint Research: 1 results) Book (1 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Preliminary Results of Branch Level, Brachial Plexus Peripheral Nerve Stimulation on a Non-Human Primate2023

    • Author(s)
      Fortune Benjamin C.、Yan Tianfang、Kaiju Taro、Suzuki Takafumi、Hirata Masayuki
    • Journal Title

      Annu Int Conf IEEE Eng Med Biol Soc

      Volume: - Pages: 1-5

    • DOI

      10.1109/embc40787.2023.10340246

    • Related Report
      2023 Annual Research Report
  • [Presentation] Preliminary Results of Branch Level, Brachial Plexus Peripheral Nerve Stimulation on a Non-Human Primate2023

    • Author(s)
      Benjamin C. Fortune, Tianfang Yan, Taro Kaiju, Takafumi Suzuki, Masayuki Hirata
    • Organizer
      45th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 機能的脳神経外科が開拓する新たな領域2023

    • Author(s)
      平田雅之
    • Organizer
      日本脳神経外科学会第82回学術総会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 植込み型ブレインマシンインターフェースの実用化への道のり2023

    • Author(s)
      平田雅之
    • Organizer
      日本脳神経外科学会第82回学術総会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Feasibility Study of Electrical Stimulation at the Brachial Plexus on a Non-human Primate2022

    • Author(s)
      FORTUNE Benjamin、平田雅之
    • Organizer
      第9回日本BMI研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 植込み神経治療デバイスの薬機戦略、治験2022

    • Author(s)
      平田雅之
    • Organizer
      第9回日本BMI研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 植込み型機能的電気刺激による運動機能再建: 新規脳神経外科治療の可能性2022

    • Author(s)
      平田雅之、Fortune Benjamin、Yan Tianfang、江村拓人、鈴木隆文、海住太郎、野村泰伸、Milocevic Matija
    • Organizer
      日本脳神経外科学会 第81回学術総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Implantable Brain Machine Interface2022

    • Author(s)
      Masayuki Hirata
    • Organizer
      The CiNnet Friday lunch seminar
    • Related Report
      2022 Annual Research Report
  • [Book] Annual Review 神経 20232023

    • Author(s)
      平田雅之
    • Total Pages
      6
    • Publisher
      中外医学社
    • ISBN
      9784498428003
    • Related Report
      2023 Annual Research Report
  • [Patent(Industrial Property Rights)] コネクタ取付具およびコネクタ部材2023

    • Inventor(s)
      平田雅之, Fortune C.B, Yan T
    • Industrial Property Rights Holder
      国立大学法人大阪大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Related Report
      2023 Annual Research Report
  • [Patent(Industrial Property Rights)] 機能的電気刺激装置および機能的電気刺激システム2023

    • Inventor(s)
      平田雅之, Fortune C.B, Yan T
    • Industrial Property Rights Holder
      国立大学法人大阪大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Related Report
      2023 Annual Research Report

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Published: 2022-02-08   Modified: 2024-12-25  

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