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Design and Development of selfpowered intelligent contact lens with 2D-MOS2 for Ocular Diagnostic

Research Project

Project/Area Number 22KF0342
Project/Area Number (Other) 22F21367 (2022)
Research Category

Grant-in-Aid for JSPS Fellows

Allocation TypeMulti-year Fund (2023)
Single-year Grants (2022)
Section外国
Review Section Basic Section 90130:Medical systems-related
Research InstitutionTokai University

Principal Investigator

槌谷 和義  東海大学, 工学部, 教授 (50399086)

Co-Investigator(Kenkyū-buntansha) JAISWAL JYOTI  東海大学, 工学部, 外国人特別研究員
Project Period (FY) 2023-03-08 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2023: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2022: ¥1,200,000 (Direct Cost: ¥1,200,000)
KeywordspH / MoS2 / Self power sensor / Contct lens / PVDF / piezoelectric properties / nanosheets / MoS2-PVDF
Outline of Research at the Start

In this study, we will not measure IOP with a single sensor, but with multiple small sensors to measure the entire eye, aiming f
or sensing with high spatial resolution. If this becomes possible, the relationship between visual field and intraocular pressure will become clear.

Outline of Annual Research Achievements

Significant progress has been made in the development of self-powered intelligent contact lenses. Achievements include successful development of a PDMS contact lens fabrication recipe, fabrication of few-layered MoS2 nanosheets, and investigation of their piezoelectric properties. Results show enhanced piezoelectricity in MoS2-PVDF nanosheets compared to pristine-MoS2 and pristine-PVDF nanosheets. Transparent conducting polymer PEDOT:PSS thin films were deposited as contact electrodes, with ongoing efforts to improve coating uniformity and transparency. Challenges remain in developing uniform PEDOT:PSS transparent conducting layer, which will be addressed by a Master student as a future work. Additionally, work was done on microneedle, microfluidic, and e-skin pH sensors throughout the JSPS period.

Report

(2 results)
  • 2023 Annual Research Report
  • 2022 Annual Research Report
  • Research Products

    (14 results)

All 2024 2023

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results) Presentation (10 results) (of which Int'l Joint Research: 7 results)

  • [Journal Article] Fabrication of microfluidic pH sensing chip based on sputtered Sb2O3/Sb thin film working electrode and AgIO3/Ag thin film reference electrode for detection of A549 cells2024

    • Author(s)
      1.Jyoti Jaiswal, Kazuma Sasaki, Kenta Shinha, Ganesh Kumar Mani, Hiroshi Kimura, and Kazuyoshi Tsuchiya
    • Journal Title

      Measurement

      Volume: 233 Pages: 114781-114781

    • DOI

      10.1016/j.measurement.2024.114781

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Highly sensitive on-skin flexible Sb2O3/Sb thin film pH sensor for real-time sweat sensing2024

    • Author(s)
      2.Jyoti Jaiswal, Souta Mizushima, Saeka Kanno, Kazuma Sasaki, Kazuya Kabayama, Kazuko Kaneda-Nakashima, Yuichiro Tsuyuki, and Kazuyoshi Tsuchiya
    • Journal Title

      Materials Research Bulletin

      Volume: 175 Pages: 112795-112795

    • DOI

      10.1016/j.materresbull.2024.112795

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of Miniaturized Microneedle Potentiometric Sensors for Real-Time LabelFree pH Detection using AgIO3/Ag/PTFE/WO3/W2024

    • Author(s)
      3.Jyoti Jaiswal, Nishijima Satoshi, Tadahiko Matsubara, Keiji Matsubara and Kazuyoshi Tsuchiya
    • Journal Title

      IEEE Transactions on Instrumentation & Measurement

      Volume: 73 Pages: 19-19

    • DOI

      10.1109/tim.2023.3347783

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Vertically Aligned Porous VxOy Nanofilms with Pt Decoration for Sub-ppm H2 Gas Sensors2023

    • Author(s)
      4.Jyoti Jaiswal, Abhijeet Das, Vivek Chetry, Sanjeev Kumar, Ramesh Chandra, Kazuyoshi Tsuchiya
    • Journal Title

      ACS Applied Nano Materials

      Volume: 6 Issue: 4 Pages: 26462657-26462657

    • DOI

      10.1021/acsanm.2c05058

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Development of a microfluidic pH sensing chip with sputtered Sb2O3/Sb thin film working electrode and AgIO3/Ag thin film reference electrode for A549 cancer cell detection2023

    • Author(s)
      Jyoti Jaiswal, Kazuyoshi Tsuchiya
    • Organizer
      The 15th Meeting of Tokai University Micro/Nano Enlightenment (Tμne)
    • Related Report
      2023 Annual Research Report
  • [Presentation] Miniaturized microneedle pH sensors based on AgCl/Ag/PTFE/ZnO/Zn for realtime intracellular pH measurement in micro-sized cells2023

    • Author(s)
      Jyoti Jaiswal, Kazuyoshi Tsuchiya
    • Organizer
      International Conference on Functional Material Applications (ICFMA2023)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Electrospun PVDF-TrFE/MoS2 nanocomposite fibres for piezoelectric energy harvesting applications2023

    • Author(s)
      Jyoti Jaiswal, Kazuyoshi Tsuchiya
    • Organizer
      34th Annual General Meeting of MRSI and the 5th Indian Materials Conclave (MRSI-AGM 2023)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of Miniaturized Microneedle pH Sensors Based on Zinc Oxide for Real-Time pH Sensing of Various Micro-Sized Biological Cells2023

    • Author(s)
      Jyoti Jaiswal, Kazuyoshi Tsuchiya
    • Organizer
      34th 2023 International Symposium on Micro-NanoMechatronics and Human Science (MHS2023)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The Impact of MoS2 nanosheets Inclusion on the Piezoelectric Energy Harvesting Performance of Electrospun PVDF-TrFE/MoS2 Nanocomposite Fiber Mats2023

    • Author(s)
      Jyoti Jaiswal, Kazuyoshi Tsuchiya
    • Organizer
      Integrated Nanocomposites for Thermal and Kinetic Energy Harvesting (INTAKE Seminar 2023)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Real-Time Sweat Sensing: A Flexible On-Skin pH Sensor Utilizing Sb2O3/Sb Thin Film Technology2023

    • Author(s)
      Jyoti Jaiswal, Souta Mizushima, Saeka Kanno, Kazuma Sasaki, Kazuya Kabayama, Kazuko Kaneda-Nakashima, Yuichiro Tsuyuki, and Kazuyoshi Tsuchiya
    • Organizer
      2023 Japan Society for Precision Engineering Fall Conference Academic Lecture
    • Related Report
      2023 Annual Research Report
  • [Presentation] Design and Fabrication of AgIO3/Ag/PTFE/WO3/W-based Microneedle Potentiometric Sensors for Real-time, Direct, Label-Free pH Detection of Innumerable Cells2023

    • Author(s)
      Jyoti Jaiswal, Nishijima Satoshi, Tadahiko Matsubara, Keiji Matsubara, Kazuyoshi Tsuchiya
    • Organizer
      2023 Japan Society for Precision Engineering Fall Conference Academic Lecture
    • Related Report
      2023 Annual Research Report
  • [Presentation] Design and Development of Miniaturized Microfluidic pH Sensors based on Sb/Sb2O3 for Biomedical Applications2023

    • Author(s)
      Jyoti Jaiswal, Ganesh Kumar mani, Kazuyoshi Tsuchiya
    • Organizer
      International Conference on Precision Engineering and Sustainable Manufacturing 2023 (PRESM2023)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Design and Fabrication of Minimally Invasive Microneedle Sensors based on WO3 for monitoring pH of Innumerable Cells2023

    • Author(s)
      Jyoti Jaiswal, Nishijima Satoshi, Kazuyoshi Tsuchiya
    • Organizer
      7th International Conference on Microneedles (MICRONEEDLES 2023)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Room temperature H2 gas sensing properties of optimal Pt-draped vertical VOx porous thin films for early hazard detection of lithium-ion battery system2023

    • Author(s)
      Jyoti Jaiswal, Kazuyoshi Tsuchiya
    • Organizer
      The 19th International Conference on Precision Engineering (ICPE 2022)
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research

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Published: 2022-09-29   Modified: 2024-12-25  

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