| Project/Area Number |
22KF0398
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| Project/Area Number (Other) |
21F21793 (2021-2022)
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| Research Category |
Grant-in-Aid for JSPS Fellows
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| Allocation Type | Multi-year Fund (2023)
Single-year Grants (2021-2022) |
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| Section | 外国 |
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| Review Section |
Basic Section 39040:Plant protection science-related
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| Research Institution | Institute of Physical and Chemical Research |
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Principal Investigator |
白須 賢 国立研究開発法人理化学研究所, 環境資源科学研究センター, グループディレクター (20425630)
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| Co-Investigator(Kenkyū-buntansha) |
NGOU POK MAN 国立研究開発法人理化学研究所, 環境資源科学研究センター, 外国人特別研究員
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| Project Period (FY) |
2023-03-08 – 2024-03-31
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| Project Status |
Completed (Fiscal Year 2023)
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| Budget Amount *help |
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 2023: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2022: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2021: ¥400,000 (Direct Cost: ¥400,000)
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| Keywords | Plant immunity / PRR / bioinformatics / nematode / evolution / pattern-recognition / receptors |
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| Outline of Research at the Start |
病害虫の認識は植物免疫機構において最も重要なステップである。本研究は植物免疫を誘導する病害虫由来物質の同定と、それを認識する植物の受容体を同定することを目的としている。植物の病害虫認識機構を分子レベルで理解することができれば、病害虫に対する植物免疫機構の全貌解明への大きな糸口となるだけでなく、新規の病害コントール法の確立につながる。
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| Outline of Annual Research Achievements |
Cell-surface receptors are involved in many biological processes, including immunity and development. It was unclear how these receptors evolve to become specialized in different biological processes. I analyzed more than 200,000 cell-surface receptors from 350 genomes, and traced the origin of immune-specific receptor-like proteins (RLPs) in plants. I discovered that the motifs required for co-receptor interaction in RLPs are related to those of the receptor-like kinase (RLKs), which perceives phytohormones and controls growth and development. These data suggest that the immunity- and development-receptors share a common origin. This work also shows that plants have evolved to perceive different environmental signals to activate the appropriate responses.
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