生体流れに関わる疾患の診断・治療・予防のための計算ナノバイオメカニクスの新展開

• Project/Area Number: 23220012
• Research Category: Grant-in-Aid for Scientific Research (S)
• Allocation Type: Single-year Grants
• Research Field: Biomedical engineering/Biological material science
• Research Institution: Tohoku University
• Principal Investigator: 山口 隆美 東北大学, 医工学研究科, 名誉教授 (30101843)
• Co-Investigator(Kenkyū-buntansha): 大森 俊宏 東北大学, 工学研究科, 助教 (10633456) ; 沼山 恵子 東北大学, 医工学研究科, 准教授 (30400287) ; 今井 陽介 東北大学, 工学研究科, 助教 (60431524) ; 上野 裕則 愛知教育大学, 教育学部, 講師 (70518240)
• Project Period (FY): 2011-05-31 – 2014-03-31
• Project Status: Discontinued (Fiscal Year 2013)
• Budget Amount: ¥153,660,000 (Direct Cost: ¥118,200,000、Indirect Cost: ¥35,460,000); Fiscal Year 2013: ¥30,940,000 (Direct Cost: ¥23,800,000、Indirect Cost: ¥7,140,000); Fiscal Year 2012: ¥61,880,000 (Direct Cost: ¥47,600,000、Indirect Cost: ¥14,280,000); Fiscal Year 2011: ¥60,840,000 (Direct Cost: ¥46,800,000、Indirect Cost: ¥14,040,000)
• Keywords: 計算生体力学 / 循環器 / 消化器 / 呼吸器 / マラリア

Research Abstract

平成25年度（平成25年4月1日～平成25年4月25日）の研究内容は，細胞スケールにおける生体力学および分子生物学の融合を目指したシミュレーション技術の開発であり，主な成果は以下のとおりである．
(1) 平成24年度に開発した細胞の接着に関連するligand-receptor結合の計算力学モデルについて，これを格子ボルツマン法と有限要素法に基づく流体－膜連成計算手法へと導入し，血小板血栓形成，マラリア感染赤血球の血管内皮細胞上の回転運動，がん細胞の血管内皮細胞への接着を対象としたシミュレーション手法の開発に着手した．
(2) 平成24年度にクライオ電子線トモグラフィー法を用いて解明した気管繊毛の三次元内部構造を考慮し，ダイニン分子の滑り運動に由来する個々の気管繊毛の運動と，これによって駆動される周囲の流れ場の連成シミュレーション手法の開発に着手した．
(3) 平成24年度までに赤血球の希薄・準希薄懸濁液を対象として，境界要素法と有限要素法に基づく流体－膜連成計算手法を開発し，循環器のマクロスケールの解析で必要となる粒子応力テンソル，自己拡散テンソルを算出している．これを赤血球濃厚懸濁液へと拡張するため，細胞濃厚懸濁液を対象とした大規模GPUシミュレーション手法の開発に着手した．
(4) 平成24年度に開発した実形状の胃に対する液体食物流動（食物攪拌）の計算力学モデルについて，これを相の異なる液体や固体運動を連成する手法へと改良し，様々な食物および胃液などの流動を解析するための計算力学モデルの開発に着手した．

Current Status of Research Progress

Reason

25年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

25年度が最終年度であるため、記入しない。

Research Products

• [Journal Article] Antral recirculation in the stomach during gastric mixing (2013)
  • Author(s): Y.Imai
  • Journal Title: American Journal of Physiology Gastrointestinal and Liver Physiology Volume: 304 Issue: 5 Pages: G536-G542
  • DOI: 10.1152/ajpgi.00350.2012
  • Peer Reviewed
• [Journal Article] Membrane tension of red blood cells pairwisely interacting in simple shear flow (2013)
  • Author(s): T.Omori
  • Journal Title: Journal of Biomechanics Volume: 46 Issue: 3 Pages: 548-553
  • DOI: 10.1016/j.jbiomech.2012.09.017
  • Peer Reviewed
• [Journal Article] Tension of red blood cell membrane in simple shear flow (2012)
  • Author(s): T.Omori
  • Journal Title: Phisical Review E Volume: 86 Issue: 5 Pages: 56321-56321
  • DOI: 10.1103/physreve.86.056321
  • Peer Reviewed
• [Journal Article] Quantification of red blood cell deformation at high-hematocrit blood flow in microvessels (2012)
  • Author(s): D. Alizadehrad
  • Journal Title: Journal of Biomechanics Volume: 45 Issue: 15 Pages: 2684-2689
  • DOI: 10.1016/j.jbiomech.2012.08.026
  • Peer Reviewed
• [Journal Article] Separation of cancer cells from a red blood cell suspension using inertial force (2012)
  • Author(s): T.Tanaka
  • Journal Title: Lab on a Chip Volume: 12 Issue: 21 Pages: 4336-4343
  • DOI: 10.1039/c2lc40354d
  • Peer Reviewed
• [Journal Article] Computational analysis on the mechanical interaction between a thrombus and red blood cells: Possible causes of membrane damage of red blood cells at microvessel (2012)
  • Author(s): Hiroki Kamada, Yohsuke Imai, Masanori Nakamura, Takuji Ishikawa, Takami Yamaguchi
  • Journal Title: Medical Engineering and Physic Volume: 34 Issue: 10 Pages: 1411-1420
  • DOI: 10.1016/j.medengphy.2012.01.003
  • Peer Reviewed
• [Journal Article] Patient-specific modelling of pulmonary airflow using GPU cluster for the application in medical practice (2012)
  • Author(s): T.Miki
  • Journal Title: Computer Methods in Biomechanics and Biomedical Engineering Volume: (in press) Issue: 7 Pages: 771-778
  • DOI: 10.1080/10255842.2011.560842
  • Peer Reviewed
• [Journal Article] Mouse respiratory cilia with the asymmetric axonemal structure on sparsely distributed ciliary cells can generate overall directional flow (2012)
  • Author(s): Hironori Ueno, et al
  • Journal Title: Nanomedicine : Nanotechnology, Biology, and Medicine Volume: (未定)(In press) Issue: 7 Pages: 1081-1087
  • DOI: 10.1016/j.nano.2012.01.004
  • Peer Reviewed
• [Journal Article] Hemodynamics in the pulmonary artery of a patient with pneumothorax (2012)
  • Author(s): J.J.Christophe
  • Journal Title: Medical Engineering & Physics Volume: (in press) Issue: 6 Pages: 725-732
  • DOI: 10.1016/j.medengphy.2011.09.016
  • Peer Reviewed
• [Journal Article] Deposition of micrometer particles in pulmonary airways during inhalation and breath holding (2012)
  • Author(s): Y. Imai
  • Journal Title: Journal of Biomechanics Volume: 45 Issue: 10 Pages: 1809-1815
  • DOI: 10.1016/j.jbiomech.2012.04.017
  • Peer Reviewed
• [Journal Article] Reorientation of a non-spherical capsule in creeping shear flow (2012)
  • Author(s): 大森俊宏
  • Journal Title: Physical Review Letters Volume: 108 Issue: 13 Pages: 128102-128102
  • DOI: 10.1103/physrevlett.108.138102
  • Peer Reviewed
• [Journal Article] Inertial migration of cancer cells in blood flow in microchannels (2012)
  • Author(s): T.Tanaka
  • Journal Title: Biomed Microdevices Volume: 14 Issue: 1 Pages: 25-33
  • DOI: 10.1007/s10544-011-9582-y
  • Peer Reviewed
• [Journal Article] Parallel Simulation of Cellular Flow in Microvessels Using a Particle Method (2012)
  • Author(s): D.Alizadehrad
  • Journal Title: Journal of Biomechanical Science and Engineering Volume: 7 Issue: 1 Pages: 57-71
  • DOI: 10.1299/jbse.7.57
  • NAID: 130002066878
  • ISSN: 1880-9863
  • Peer Reviewed
• [Journal Article] Margination of red blood cells infected by Plasmodium falciparum in a microvessel (2011)
  • Author(s): Y.Imai
  • Journal Title: Journal of Biomechanics Volume: 44 Issue: 8 Pages: 1553-1558
  • DOI: 10.1016/j.jbiomech.2011.02.084
  • Peer Reviewed
• [Journal Article] ransport phenomena of microbial flora in the small intestine with peristalsi (2011)
  • Author(s): T.Ishikawa
  • Journal Title: Journal of Theoretical Biology Volume: 279 Issue: 1 Pages: 63-73
  • DOI: 10.1016/j.jtbi.2011.03.026
  • Peer Reviewed
• [Journal Article] Energy Transport in a Concentrated Suspension of Bacteria (2011)
  • Author(s): Takuji Ishikawa, et al
  • Journal Title: Physical Review Letters Volume: 107 Issue: 2
  • DOI: 10.1103/physrevlett.107.028102
  • Peer Reviewed
• [Journal Article] Comparison between spring network models and continuum constitutive laws : application to the large deformation of a capsule in shear flow (2011)
  • Author(s): T.Omori
  • Journal Title: Physical Review E Volume: 83 Issue: 4
  • DOI: 10.1103/physreve.83.041918
  • Peer Reviewed
• [Journal Article] Development of a particle interaction kernel for convection-diffusion scalar transport equation (2011)
  • Author(s): C.Huang
  • Journal Title: Numerical Heat Transfer, Part B : Fundamentals Volume: 60 Issue: 2 Pages: 96-115
  • DOI: 10.1080/10407790.2011.594389
  • Peer Reviewed
• [Journal Article] Computational study on effect of stenosis on primary thrombus formation (2011)
  • Author(s): H.Kamada
  • Journal Title: Biorheology Volume: 48 Issue: 2 Pages: 99-114
  • DOI: 10.3233/bir-2011-0585
  • Peer Reviewed
• [Journal Article] Asymmetry of red blood cell motions in a microchannel with a diverging and converging bifurcation (2011)
  • Author(s): V.Leble
  • Journal Title: Biomicrofluidics Volume: 5 Issue: 4
  • DOI: 10.1063/1.3672689
  • Peer Reviewed
• [Journal Article] Orientational order in concentrated suspensions of spherical microswimmers (2011)
  • Author(s): A.Evans
  • Journal Title: Physics of Fluids Volume: 23 Issue: 11
  • DOI: 10.1063/1.3660268
  • Peer Reviewed
• [Presentation] Computational biomechanics of blood flow from cellular to organ scales (2013)
  • Author(s): T. Yamaguchi
  • Organizer: Advances in Computational Mechanics (ACM 2013) ― A Conference Celebrating the 70th Birthday of Thomas J.R. Hughes
  • Place of Presentation: San Diego, California, USA
  • Invited
• [Presentation] Application of GPU computing to physiological flow simulations (2013)
  • Author(s): Y. Imai
  • Organizer: Advances in Computational Mechanics (ACM 2013) ― A Conference Celebrating the 70th Birthday of Thomas J.R. Hughes
  • Place of Presentation: San Diego, California, USA
  • Invited
• [Presentation] Computational Biomechanics of Physiological Flows in the Cardiovascular, Respiratory, and Digestive systems (2013)
  • Author(s): T. Yamaguchi
  • Organizer: International Symposium on Bio Medical Engineering Interface
  • Place of Presentation: Sendai, Japan
  • Invited
• [Presentation] A particle model of cellular flow in microcirculation (2012)
  • Author(s): T.Yamaguchi
  • Organizer: 18th International Symposium of Tohoku University Global COE Program "Global Nano-Biomedical Engineering Education and Research Network Centre"
  • Place of Presentation: Sendai, Japan
  • Year and Date: 2012-03-06
• [Presentation] Collective diffusion of red blood cells from high concentration to low (2012)
  • Author(s): C.Chuang
  • Organizer: 18th International Symposium of Tohoku University Global COE Program "Global Nano-Biomedical Engineering Education and Research Network Centre"
  • Place of Presentation: Sendai, Japan
  • Year and Date: 2012-03-06
• [Presentation] Quantifying Characteristics of Red Blood Cell at Dense Cellular Flow (2012)
  • Author(s): D.Alizadehrad
  • Organizer: 18th International Symposium of Tohoku University Global COE Program "Global Nano-Biomedical Engineering Education and Research Network Centre"
  • Place of Presentation: Sendai, Japan
  • Year and Date: 2012-03-06
• [Presentation] Hydrodynamic Entrapment of Ciliates at the Interface Fluid-air (2012)
  • Author(s): J.Ferracci
  • Organizer: 18th International Symposium of Tohoku University Global COE Program "Global Nano-Biomedical Engineering Education and Research Network Centre
  • Place of Presentation: Sendai, Japan
  • Year and Date: 2012-03-06
• [Presentation] Effect of Constitutive Law on the Lateral Migration of a Capsule Near a Wall (2012)
  • Author(s): S.Nix
  • Organizer: 18th International Symposium of Tohoku University Global COE Program "Global Nano-Biomedical Engineering Education and Research Network Centre"
  • Place of Presentation: Sendai, Japan
  • Year and Date: 2012-03-06
• [Presentation] A numerical study on the RBC deformation in high-hematocrit conditions in microvessels (2012)
  • Author(s): D. Alizadehrad
  • Organizer: 10th International Symposium on Biomechanics and Biomedical Engineering 2012
  • Place of Presentation: Berlin, Germany
• [Presentation] Energy efficiency in collective motions of swimming bacteria (2012)
  • Author(s): T. Ishikawa
  • Organizer: 2012 World Congress on Medical Physics and Biomedical Engineering
  • Place of Presentation: Beijing, China
• [Presentation] Providing a human user artificial ability to control their eyes independently with various eye movement patterns (2012)
  • Author(s): F. Mizuno
  • Organizer: 13th International Multisensory Research Forum
  • Place of Presentation: Oxford, United Kingdom
• [Presentation] Double-layer representation of model microorganisms by a boundary element method (2012)
  • Author(s): K. Kyoya
  • Organizer: ASME 2012 Summer Bioengineering Conference (SBC2012)
  • Place of Presentation: Fajardo, Puerto Rico
• [Presentation] Development of a multi-phase flow model for simulating solid particle motion in the stomach (2012)
  • Author(s): T. Miyagawa
  • Organizer: ASME 2012 Summer Bioengineering Conference (SBC2012)
  • Place of Presentation: Fajardo, Puerto Rico
• [Presentation] Development of a numerical model for micro-scale blood flow simulation using GPGPU (2012)
  • Author(s): N. Takeishi
  • Organizer: ASME 2012 Summer Bioengineering Conference (SBC2012)
  • Place of Presentation: Fajardo, Puerto Rico
• [Presentation] Dynamics of a spherical capsule in a near-wall shear flow (2012)
  • Author(s): S. Nix
  • Organizer: ASME 2012 Summer Bioengineering Conference (SBC2012)
  • Place of Presentation: Fajardo, Puerto Rico
• [Presentation] Analysis of ciliary motion and the axonemal structure in the mouse respiratory cilia (2012)
  • Author(s): H. Ueno
  • Organizer: ASME 2012 Summer Bioengineering Conference (SBC2012)
  • Place of Presentation: Fajardo, Puerto Rico
• [Presentation] Boundary element analysis of the multi-capsule flow using an ultra-high speed GPGPU computation (2012)
  • Author(s): D. Matsunaga
  • Organizer: 34th International Conference on Boundary Elements and other Mesh Reduction Methods
  • Place of Presentation: Split, Croatia
• [Presentation] Boundary element analysis of deformation and movement of a capsule and a red blood cell close to the wall (2012)
  • Author(s): S. Nix
  • Organizer: 34th International Conference on Boundary Elements and other Mesh Reduction Methods
  • Place of Presentation: Split, Croatia
• [Presentation] Multi-GPU computing of capsule dense suspension using boundary element method (2012)
  • Author(s): D. Matsunaga
  • Organizer: Softflow 2012 - Biological Complex Fluids
  • Place of Presentation: Cargese, France
• [Presentation] Development of a numerical model for microcirculatory blood flow simulation on GPU (2012)
  • Author(s): N. Takeishi
  • Organizer: Softflow 2012 - Biological Complex Fluids
  • Place of Presentation: Cargese, France
• [Presentation] Dynamics of capsules near a plane wall (2012)
  • Author(s): S. Nix
  • Organizer: Softflow 2012 - Biological Complex Fluids
  • Place of Presentation: Cargese, France
• [Presentation] Hydrodynamic entrapment of ciliates at the air-liquid interface (2012)
  • Author(s): J. Ferracci
  • Organizer: Softflow 2012 - Biological Complex Fluids
  • Place of Presentation: Cargese, France
• [Presentation] Particle based simulation of microcirculation using a parallel computation (2012)
  • Author(s): T. Yamaguchi
  • Organizer: 14th International Congress of Biorheology and 7th International Conference of Clinical Hemorheology (ISB and ISCH)
  • Place of Presentation: Istanbul, Turkey
• [Presentation] Reorientation of a non-spherical micro-capsule in shear flow (2012)
  • Author(s): T. Ishikawa
  • Organizer: 23rd International Congress of Theoretical and Applied Mechanics
  • Place of Presentation: Beijing, China
• [Presentation] Fundamental Study on a method to provide independent fields of view to eyes (2012)
  • Author(s): F. Mizuno
  • Organizer: 34th Annual International Conference of the IEEE Engineering in Medicine & Biology Society
  • Place of Presentation: San Diego, California, USA
• [Presentation] Computational analysis on the mechanical interaction between a thrombus and red blood cells (2012)
  • Author(s): H. Kamada
  • Organizer: 6th EUROPEAN CONGRESS ON COMPUTATIONAL METHODS IN APPLIED SCIENCES AND ENGINEERING (ECCOMAS 2012)
  • Place of Presentation: Vienna, Austria
• [Presentation] Role of fluid mechanics in collective motions of bacteria (2012)
  • Author(s): T. Ishikawa
  • Organizer: Ninth International Conference on Flow Dynamics
  • Place of Presentation: Sendai, Japan
  • Invited
• [Presentation] Computational biomechanics of physiological flows over micro to macro scales (2012)
  • Author(s): T. Yamaguchi
  • Organizer: 2012 Northeastern Asian Symposium on "Biomaterial and Nano-bio Thechnology"
  • Place of Presentation: Sendai, Japan
  • Invited
• [Presentation] Development of a GPU-Implemented BEM solver for biological cell suspensions (2012)
  • Author(s): Y. Imai
  • Organizer: JSME-CMD ICMS2012 in Kobe
  • Place of Presentation: Kobe, Japan
• [Presentation] Lateral migration of capsules in a near-wall shear flow (2012)
  • Author(s): S. Nix
  • Organizer: JSME-CMD ICMS2012 in Kobe
  • Place of Presentation: Kobe, Japan
• [Presentation] Hydrodynamical entrapment of ciliates at the air-liquid interface (2012)
  • Author(s): J. Ferracci
  • Organizer: American Physical Society 65th Annual DFD Meeting
  • Place of Presentation: San Diego, California, USA
• [Presentation] Gradient diffusion of red blood cells in blood flow through a Y-shape microchannel (2012)
  • Author(s): C. Chuang
  • Organizer: American Physical Society 65th Annual DFD Meeting
  • Place of Presentation: San Diego, California, USA
• [Presentation] 3D-PTV measurement of the phototactic movement of algae in shear flow (2012)
  • Author(s): T. Maeda
  • Organizer: American Physical Society 65th Annual DFD Meeting
  • Place of Presentation: San Diego, California, USA
• [Presentation] Analysis of Red Blood Cell Behavior in a Narrow Tube (2012)
  • Author(s): H. Hosaka
  • Organizer: American Physical Society 65th Annual DFD Meeting
  • Place of Presentation: San Diego, California, USA
• [Presentation] Off-plane motion of a non-spherical capsule in simple shear flow (2012)
  • Author(s): T. Omori
  • Organizer: American Physical Society 65th Annual DFD Meeting
  • Place of Presentation: San Diego, California, USA
• [Presentation] Measurement of ciliary flow generated on the surface of tracheal (2012)
  • Author(s): K. Kiyota
  • Organizer: American Physical Society 65th Annual DFD Meeting
  • Place of Presentation: San Diego, California, USA
• [Presentation] Entrapment of fresh water ciliates at the interface fluid-air (2011)
  • Author(s): J.Ferracci
  • Organizer: 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
  • Place of Presentation: National University of Singapore, Singapore
  • Year and Date: 2011-12-14
• [Presentation] Multi-GPU computing of capsule flow using boundary integral method (2011)
  • Author(s): D.Matsunaga
  • Organizer: 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
  • Place of Presentation: National University of Singapore, Singapore
  • Year and Date: 2011-12-13
• [Presentation] Computation of near-wall capsule flow using boundary integral method (2011)
  • Author(s): S.Nix
  • Organizer: 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
  • Place of Presentation: National University of Singapore, Singapore
  • Year and Date: 2011-12-13
• [Presentation] Transport phenomena in suspensions of swimming microorganisms (2011)
  • Author(s): T.Ishikawa
  • Organizer: 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
  • Place of Presentation: National University of Singapore, Singapore(招待講演)
  • Year and Date: 2011-12-13
• [Presentation] Development of a micro fluidic device to separate motile bacteria (2011)
  • Author(s): T.Shioiri
  • Organizer: 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
  • Place of Presentation: National University of Singapore, Singapore
  • Year and Date: 2011-12-12
• [Presentation] Collective diffusion of red blood cells from high concentration to low (2011)
  • Author(s): C.Chuang
  • Organizer: 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
  • Place of Presentation: National University of Singapore, Singapore
  • Year and Date: 2011-12-12
• [Presentation] Analysis of fluid flow on the surface of tracheal lumen through effective ciliary motion (2011)
  • Author(s): K.Kiyota
  • Organizer: 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
  • Place of Presentation: National University of Singapore, Singapore
  • Year and Date: 2011-12-12
• [Presentation] Energy transport in a concentrated suspension of bacteria (2011)
  • Author(s): T.Ishikawa
  • Organizer: 64th Annual Meeting of the American Physical Society's Division of Fluid Dynamics (DFD)
  • Place of Presentation: Baltimore, MD, USA
  • Year and Date: 2011-11-20
• [Presentation] EInstabilities and global order in concentrated suspensions of spherical microswimmers (2011)
  • Author(s): A.Evans
  • Organizer: 64th Annual Meeting of the American Physical Society's Division of Fluid Dynamics (DFD)
  • Place of Presentation: Baltimore, MD, USA
  • Year and Date: 2011-11-20
• [Presentation] Analysis of ciliary motion and the axonemal structure in the mouse respiratory cilia (2011)
  • Author(s): H.Ueno
  • Organizer: The 5th Shanghai International Conference on Biophysics and Molecular Biology
  • Place of Presentation: Shanghai, China(招待講演)
  • Year and Date: 2011-11-06
• [Presentation] Development of GPU computing for simulating dense suspension of capsules (2011)
  • Author(s): Y.Imai
  • Organizer: The 5th Shanghai International Conference on Biophysics and Molecular Biology
  • Place of Presentation: Shanghai, China(招待講演)
  • Year and Date: 2011-11-06
• [Presentation] Development of a microdevice for sorting motile bacteria (2011)
  • Author(s): T.Shioiri
  • Organizer: ASME 2011 6th Frontiers in Biomedical Devices Conference
  • Place of Presentation: Irvine, California, USA
  • Year and Date: 2011-09-27
• [Presentation] Collection of cancer cells from blood samples using inertial migration forces (2011)
  • Author(s): T.Tanaka
  • Organizer: ASME 2011 6th Frontiers in Biomedical Devices Conference
  • Place of Presentation: Irvine, California, USA
  • Year and Date: 2011-09-26
• [Presentation] Modelling of red blood cell motion and deformation using particle based method (2011)
  • Author(s): T.Yamaguchi
  • Organizer: Simulation and Modeling of Biological Flows (SIMBIO 2011)
  • Place of Presentation: Brussels, Belgium
  • Year and Date: 2011-09-22
• [Presentation] Swallowing simulation based on videofluorography (2011)
  • Author(s): S.Ishida
  • Organizer: International Conference on BioTribology (ICoBT 2011)
  • Place of Presentation: London, UK
  • Year and Date: 2011-09-20
• [Presentation] Particle based simulation of the microvascular blood flow in the malaria infection (2011)
  • Author(s): T.Yamaguchi
  • Organizer: Trends & Challenges in Computational Mechanics (TCCM 2011)
  • Place of Presentation: Padua, Italy
  • Year and Date: 2011-09-12
• [Presentation] Particle Based Modeling and Simulation of the Red Blood Cell Infected by Malaria-Mechanism of the Margination of the Infected Red Blood Cell- (2011)
  • Author(s): T.Yamaguchi
  • Organizer: 3rd Micro and Nano Flows Conference (MNF2011)
  • Place of Presentation: Thessaloniki, Greece
  • Year and Date: 2011-08-22
• [Presentation] Numerical simulation on margination of malaria-infected red blood cells in microvessels (2011)
  • Author(s): Y.Imai
  • Organizer: Japan-Portugal Nano-BME Symposium 2011
  • Place of Presentation: Proto, Portugal
  • Year and Date: 2011-06-06
• [Presentation] Analysis of ciliary motion and fluid flow on the surface of tracheal cells (2011)
  • Author(s): H.Ueno
  • Organizer: Japan-Portugal Nano-BME Symposium 2011
  • Place of Presentation: Proto, Portugal
  • Year and Date: 2011-06-06
• [Presentation] Numerical simulation of cell depleted peripheral layer and red blood cells motion in microvascular blood flow (2011)
  • Author(s): D.Alizadehrad
  • Organizer: Japan-Portugal Nano-BME Symposium 2011
  • Place of Presentation: Proto, Portugal
  • Year and Date: 2011-06-06
• [Presentation] Gradient diffusion of red blood cells in a Y-shape microchannel (2011)
  • Author(s): C.Chuang
  • Organizer: Japan-Portugal Nano-BME Symposium 2011
  • Place of Presentation: Proto, Portugal
  • Year and Date: 2011-06-06
• [Presentation] High performance GPU computing of capsule flow using boundary integral method (2011)
  • Author(s): D.Matsunaga
  • Organizer: Japan-Portugal Nano-BME Symposium 2011
  • Place of Presentation: Proto, Portugal
  • Year and Date: 2011-06-06
• [Presentation] Computational biomechanics for respiratory and micro-circulatory systems (2011)
  • Author(s): T.Yamaguchi
  • Organizer: Japan-Portugal Nano-BME Symposium 2011
  • Place of Presentation: Proto, Portugal
  • Year and Date: 2011-06-03
• [Presentation] Capsule flow analysis using GPU computation (2011)
  • Author(s): D.Matsunaga
  • Organizer: Microscale Modeling in Biomechanics and Mechanobiology
  • Place of Presentation: Ericeira, Portugal
  • Year and Date: 2011-06-01
• [Presentation] Diffusion of red blood cells from high concentration to low in a blood flow microchannel (2011)
  • Author(s): C.Chuang
  • Organizer: Microscale Modeling in Biomechanics and Mechanobiology
  • Place of Presentation: Ericeira, Portugal
  • Year and Date: 2011-06-01
• [Presentation] Computational analysis of the margination of malaria-infected red blood cells in microcirculation (2011)
  • Author(s): T.Yamaguchi
  • Organizer: Microscale Modeling in Biomechanics and Mechanobiology
  • Place of Presentation: Ericeira, Portugal
  • Year and Date: 2011-05-31
• [Presentation] Effect of red blood cells on dynamics of microvascular blood flow (2011)
  • Author(s): D.Alizadehrad
  • Organizer: Microscale Modeling in Biomechanics and Mechanobiology
  • Place of Presentation: Ericeira, Portugal
  • Year and Date: 2011-05-31
• [Presentation] Analysis of ciliary motion and fluid flow on the surface of tracheal cells (2011)
  • Author(s): H.Ueno
  • Organizer: Microscale Modeling in Biomechanics and Mechanobiology
  • Place of Presentation: Ericeira, Portugal
  • Year and Date: 2011-05-30
• [Presentation] Inertial migration of cancer cells in high hematocrit blood flow (2011)
  • Author(s): T.Tanaka
  • Organizer: 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
  • Place of Presentation: National University of Singapore, Singapore
• [Presentation] A numerical computation on gastric mixing using GPU (2011)
  • Author(s): I.Kobayashi
  • Organizer: 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
  • Place of Presentation: National University of Singapore, Singapore
• [Presentation] GPU-based simulation of blood flow in complex microvessels (2011)
  • Author(s): K.Nakaaki
  • Organizer: 5th East Asian Pacific Student Workshop on Nano-Biomedical Engineering
  • Place of Presentation: National University of Singapore, Singapore
• [Book] Single and Two-Phase Flows on Chemical and Biomedical Engineering (2012)
  • Author(s): T. Fukui
  • Publisher: Bentham Science
• [Book] Single and Two-Phase Flows on Chemical and Biomedical Engineering (2012)
  • Author(s): R. Lima
  • Publisher: Bentham Science
• [Book] Single and Two-Phase Flows on Chemical and Biomedical Engineering (2012)
  • Author(s): Y.Feng
  • Publisher: Bentham Science
• [Book] NANO-BIOMEDICAL ENGINEERING 2012 Proceedings of the Tohoku University Global Center of Excellelce Programne Global Nano-Biomedical Engineering Education and Research Network Centre (2012)
  • Author(s): T.Yamaguchi
  • Publisher: Imperial College Press
• [Book] NANO-BIOMEDICAL ENGINEERING 2012 Proceedings of the Tohoku University Global Center of Excellelce Programne Global Nano-Biomedical Engineering Education and Research Network Centre (2012)
  • Author(s): C.Huang
  • Publisher: Imperial College Press
• [Book] NANO-BIOMEDICAL ENGINEERING 2012 Proceedings of the Tohoku University Global Center of Excellelce Programne Global Nano-Biomedical Engineering Education and Research Network Centre (2012)
  • Author(s): J.Ferracci
  • Publisher: Imperial College Press
• [Book] NANO-BIOMEDICAL ENGINEERING 2012 Proceedings of the Tohoku University Global Center of Excellelce Programne Global Nano-Biomedical Engineering Education and Research Network Centre (2012)
  • Author(s): S.Nix
  • Publisher: Imperial College Press
• [Book] NANO-BIOMEDICAL ENGINEERING 2012 Proceedings of the Tohoku University Global Center of Excellelce Programne Global Nano-Biomedical Engineering Education and Research Network Centre (2012)
  • Author(s): M.Saaadatmand
  • Publisher: Imperial College Press
• [Remarks]
  • URL: http://db.tohoku.ac.jp/whois/detail/1e0189ae4faba37c37a1d841fbb6a58b.html
• [Patent(Industrial Property Rights)] 血液中の粒子分離装置 (2012)
  • Inventor(s): 石川拓司、田中達也、沼山恵子、上野裕則、今井陽介、山口隆美
  • Industrial Property Rights Holder: 国立大学法人東北大学
  • Industrial Property Number: 2012-013612
  • Filing Date: 2012-01-26