| Budget Amount *help |
¥214,760,000 (Direct Cost: ¥165,200,000、Indirect Cost: ¥49,560,000)
Fiscal Year 2015: ¥42,640,000 (Direct Cost: ¥32,800,000、Indirect Cost: ¥9,840,000)
Fiscal Year 2014: ¥42,640,000 (Direct Cost: ¥32,800,000、Indirect Cost: ¥9,840,000)
Fiscal Year 2013: ¥42,640,000 (Direct Cost: ¥32,800,000、Indirect Cost: ¥9,840,000)
Fiscal Year 2012: ¥42,640,000 (Direct Cost: ¥32,800,000、Indirect Cost: ¥9,840,000)
Fiscal Year 2011: ¥44,200,000 (Direct Cost: ¥34,000,000、Indirect Cost: ¥10,200,000)
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| Outline of Final Research Achievements |
In meristems, stem cells proliferate to maintain their number and differentiate into specific cells. In this study we aimed at understanding the regulation of vascular stem cell fates. First, we succeeded in revealing a novel glycogen synthase 3 kinase-depending intracellular signaling pathway downstream of TDIF peptide signal, which functions in suppression of xylem differentiation. Secondly, we found a stem cell regulation mechanism in which a heterodimer of bHLH transcription factors promotes stem cell proliferation through induction of cytokinin biosynthesis-related genes. Finally, we demonstrated a mechanism in which asymmetric plasma membrane structure in developing xylem cells is produced by spontaneously activated small G protein and microtubules. This asymmetric plasma membrane structure plays a role in patterned secondary wall formation.
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