|Budget Amount *help
¥43,550,000 (Direct Cost: ¥33,500,000、Indirect Cost: ¥10,050,000)
Fiscal Year 2014: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2013: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2012: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2011: ¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
|Outline of Final Research Achievements
We studied the dynamical aspects of life accompanied by the development of physical consideration, by considering the hierarchical structure: 1) On-off switching of large number of genes embedded in genomic DNA. Biological significance of the discrete nature of the conformational transition was theoretically discussed in relation to robust on/off switching of large number of genes on the process of cell-differentiation. 2) Field hypothesis on living cell. It was shown that unique physic-chemical properties emerge in micro systems, which may concern with the life activity of living cells. 3)Novel non-Turing scenario of body-organization during development was proposed and simple theoretical modeling was successfully achieved.