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Multimodal molecular imaging system and its application for investigation of in vivo cell/tissue

Research Project

Project/Area Number 23240069
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionOsaka University

Principal Investigator

ARAKI Tsutomu  大阪大学, 基礎工学研究科, 教授 (50136214)

Co-Investigator(Kenkyū-buntansha) HASHIMOTO Mamoru  大阪大学, 大学院基礎工学研究科, 准教授 (70237949)
FUKUSHIMA Shuichiro  大阪大学, 大学院基礎工学研究科, 助教 (40362644)
NIIOKA Hirohiko  大阪大学, 大学院基礎工学研究科, 助教 (70552074)
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥49,270,000 (Direct Cost: ¥37,900,000、Indirect Cost: ¥11,370,000)
Fiscal Year 2013: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2012: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
Fiscal Year 2011: ¥26,650,000 (Direct Cost: ¥20,500,000、Indirect Cost: ¥6,150,000)
Keywordsコラーゲン / カソードルミネッセンス / SHG顕微鏡 / 分子イメージング / 細胞培養 / in vivo生体計測 / ナノ蛍光粒子 / MEMS / ラマン顕微鏡 / MEMS / カソードルミネッセンス / 顕微分光 / 蛍光量子ドット
Research Abstract

Aims of this research project are development and application of novel imaging method that can informs molecular morphology and function of biological specimens. In the present research, we have focused on the second harmonic generation (SHG) microscopy and cathode luminescence(CL) microscopy.A polarization resolved, high-speed SHG microscope was developed. In in vivo measurement with this microscope, age related dermis collagen image were observed. Also we demonstrated SHG imaging of tissue-engineered cartilage composed of rabbit chondrocytes and type I collagen gel. From this, we confirmed that it is suitable for evaluating the quality of tissue-engineered cartilage. In the CL microscopy, three kinds of rare-earth-doped nanophosphors were synthesized and injected into macrophages. The spatial distribution of nanophosphors was visualized by using a scanning electron microscope CL system.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (67 results)

All 2014 2013 2012 2011 Other

All Journal Article (19 results) (of which Peer Reviewed: 17 results) Presentation (43 results) (of which Invited: 5 results) Remarks (4 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Accumulation of advanced glycation end-products in human dentin by aging2014

    • Author(s)
      Jiro Miura, Kantaro Nishikawa, Mizuho Kubo, Shuichiro Fukushima, Mamoru Hashimoto, Fumio Takeshige, and Tsutomu Araki
    • Journal Title

      Arch Oral Biol

      Volume: Vol. 59, No. 2 Issue: 2 Pages: 119-124

    • DOI

      10.1016/j.archoralbio.2013.10.012

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Non-invasive detection of matrix-producing chondrocytes in tissue-engineered cartilage by second-harmonic-generation microscopy2014

    • Author(s)
      Reiko Maehara, Shuichiro Fukushima, Masahiro Kino-oka, Tsutomu ARAKI
    • Journal Title

      Journal of Biomechanical Science and Engineering

      Volume: 9 Issue: 1 Pages: JBSE0007-JBSE0007

    • DOI

      10.1299/jbse.2014jbse0007

    • NAID

      130003393148

    • ISSN
      1880-9863
    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Motion-artifact-robust, polarizationresolved second-harmonic-generation microscopy based on rapid polarization switching with electro-optic Pockells cell and its application to in vivo visualization of collagen fiber orientation in human facial skin2014

    • Author(s)
      Yuji. Tanaka, Tsutomu Araki, et al.
    • Journal Title

      Biomed. Opt. Express

      Volume: Vol.5 Issue: 4 Pages: 1099-1113

    • DOI

      10.1364/boe.5.001099

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Motion-artifact-robust, polarization-resolved second-harmonic-generation microscopy based on rapid polarization switching with electro-optic Pockells cell and its application to in vivo visualization of collagen fiber orientation in human facial skin2014

    • Author(s)
      Yuji. Tanaka、Tsutomu Araki, et al.
    • Journal Title

      Biomed. Opt. Express

      Volume: 5 Pages: 1099-1113

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Accumulation of advanced glycation end-products in human dentin by aging2014

    • Author(s)
      Jiro Miura, Shuichiro Fukushima, Mamoru Hashimoto, Tsutomu Araki, et al.
    • Journal Title

      Arch. Oral Biol

      Volume: 59 Pages: 119-124

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-invasive detection of matrix-producing chondrocytes in tissue-engineered cartilage by second-harmonic-generation microscopy2014

    • Author(s)
      Reiko Maehara, Shuichiro Fukushima, Tsutomu Araki, et al.
    • Journal Title

      J Biomechanical Science and Engineering

      Volume: 掲載決定

    • NAID

      130003393148

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 希土類添加ナノ蛍光体粒子を用いたカソードルミネッセンス・蛍光細胞イメージング2014

    • Author(s)
      新岡宏彦,古川太一,橋本守
    • Journal Title

      顕微鏡

      Volume: 49

    • NAID

      130007701699

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High-resolution microscopy for biological specimens via cathodoluminescence and Eu- and Zn-doped Y_2O_3 nanophosphors2013

    • Author(s)
      Taichi Furukawa, Hirohiko Niioka, Tsutomu Araki, Mamoru Hashimoto, et al
    • Journal Title

      Opt Express

      Volume: Vol. 21 Issue: 22 Pages: 25655-25663

    • DOI

      10.1364/oe.21.025655

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] in vivo observation of age- related structural changes of dermal collagen in human facial skin using collagen-sensitive second harmonic generation microscope equipped with 1250-nm mode-locked Cr:Forsterite laser2013

    • Author(s)
      T. Yasui, M. Yonetsu, R. Tanaka, Y.Tanaka, S. Fukushima, T. Yamashita, Y.Ogura, T. Hirao, H. Murota, and T. Araki
    • Journal Title

      J. Biomed. Opt

      Volume: 18 Issue: 3 Pages: 31108-31108

    • DOI

      10.1117/1.jbo.18.3.031108

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] In vivo visualization of dermal collagen fiber in skin burn by collagen-sensitive second-harmonic- generation microscopy2013

    • Author(s)
      R. Tanaka, S. Fukushima, K. Sasaki, Y.Tanaka, H. Murota, T. Matsumoto, T.Araki, and T. Yasui
    • Journal Title

      J. Biomed. Opt

      Volume: 18 Issue: 06 Pages: 61231-61231

    • DOI

      10.1117/1.jbo.18.6.061231

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Formation of a carbon nanoribbon by spontaneous collapse of a carbon nanotube grown from a γ-Fe nanoparticle via an origami mechanism2013

    • Author(s)
      Hideo Kohno, Hirohiko Niioka, et al.
    • Journal Title

      Nanoscale

      Volume: 5 Pages: 570-573

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Noninvasive in situ assessment of structural alteration of human dermis caused by photoaging using a novel collagen-specific imaging technique2013

    • Author(s)
      Toyonobu Yamashita、Tsutomu Araki, et al.
    • Journal Title

      IFSCC magazine

      Volume: 16 Pages: 3-7

    • Related Report
      2013 Annual Research Report
  • [Journal Article] SHG顕微断層偏光イメージング- SHGによるコラーゲンの可視化-2013

    • Author(s)
      橋本守, 福島修一郎, 安井武史, 荒木勉
    • Journal Title

      光アライアンス

      Volume: 24 Pages: 21-29

    • Related Report
      2013 Annual Research Report
  • [Journal Article] High-resolution microscopy for biological specimens via cathodoluminescence of Eu-and Zn-doped Y2O3 nanophosphors2013

    • Author(s)
      Taichi Furukawa, Hirohiko Niioka, Tsutomu Araki, Mamoru Hashimoto, et al.
    • Journal Title

      Opt. Express

      Volume: 21 Pages: 25655-25655

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vivo observation of age-related structural changes of dermal collagen in human facial skin using collagen sensitive second harmonic generation microscope equipped with 1250-nm mode-locked Cr:Forsterite laser2013

    • Author(s)
      Takeshi Yasui
    • Journal Title

      Journal of Biomedical Optics

      Volume: 18 Pages: 31108-31108

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vivo visualization of dermal collagen fiber in skin burn by collagen-sensitive second-harmonic-generation microscopy2013

    • Author(s)
      Ryousuke Tnaka
    • Journal Title

      Journal of Biomedical Optics

      Volume: 18

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 高速・直交偏光分解第2高調波発生光顕微鏡を用いた コラーゲン配向のin vivoイメージング2013

    • Author(s)
      田中 佑治
    • Journal Title

      生体医工学

      Volume: 51

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multicolor cathode-luminescence microscopy for biological imaging with nanophosphors2011

    • Author(s)
      Hirohiko Niioka, Tsutomu Araki, Mamoru Hashimoto, et al.
    • Journal Title

      APEX

      Volume: Vol. 4, No. 11 Issue: 11 Pages: 112402-112404

    • DOI

      10.1143/apex.4.112402

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 紫外線による肌内部ダメージを可視化する技術の開発2011

    • Author(s)
      山下 豊信
    • Journal Title

      FRANGRANCE JOURNAL

      Volume: 7 Pages: 25-31

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] カソードルミネッセンス顕微鏡と光学顕微鏡の融合2014

    • Author(s)
      新岡宏彦, 荒木勉, 橋本守, 他
    • Organizer
      顕微鏡学会分科会バイオメディカルニューマイクロスコープ
    • Place of Presentation
      帝京大学医学部
    • Year and Date
      2014-03-06
    • Related Report
      2013 Final Research Report
  • [Presentation] In situ visualization of tissue collagen by laser induced second harmonic generation light2014

    • Author(s)
      Tsutomu Araki
    • Organizer
      Japan Taiwan Bilateral Conference on Biomedical and Plasmonic Imaging
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2013 Final Research Report
  • [Presentation] In vivo time-lapse imaging of skin burn wound healing using second-harmonic generation microscopy2014

    • Author(s)
      Takeshi Yasui, Shuichiro Fukushima, Tsutomu Araki, et al.
    • Organizer
      BiOS 2014
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] 非線形光学マルチモーダル顕微鏡によるアテローム性動脈 硬化症病変の組織学的評価2014

    • Author(s)
      田尾知世, 福島修一郎, 橋本守, 荒木勉
    • Organizer
      第26回バイオエンジニアリング講演会
    • Place of Presentation
      仙台市
    • Related Report
      2013 Final Research Report
  • [Presentation] Visible to near-infrared luminescent nanoparticles for multimodal bioimaging on nanometer to millimeter scale2014

    • Author(s)
      Shoichiro Fukushima, Hirohiko Niioka,Tsutomu Araki, Mamoru Hashimoto, et al.
    • Organizer
      Japan Taiwan Bilateral Conference on Biomedical and Plasmonic Imaging
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2013 Annual Research Report
  • [Presentation] In situ visualization of tissue collagen by laser induced second harmonic generation light2014

    • Author(s)
      Tsutomu Araki
    • Organizer
      Japan Taiwan Bilateral Conference on Biomedical and Plasmonic Imaging
    • Place of Presentation
      Taipei , Taiwan
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Y2O3-based nanophosphors for multi-colored cathodoluminescence and up-conversion luminescence bioimaging2014

    • Author(s)
      Shoichio Fukushima, Hirohiko Niioka, Tsutomu Araki Mamoru Hashimoto, et al.
    • Organizer
      1st. KANSAI Nanoscience and Nanotechnology International Symposium
    • Place of Presentation
      Suita, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Synthesis of nanophosphors for correlative cathodoluminescence, up-conversion, and near-infrared bioimaging2014

    • Author(s)
      Schoichiro Fukushima, Hirohiko Niioka,Tsutomu Araki, Mamoru Hashimoto, et al.
    • Organizer
      UK-Japan workshop on Nanophotonics, Metamaterials and Plasmonics
    • Place of Presentation
      Suita, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Cathodoluminescence imaging for cells with using nanophosphor probes and scanning transmission electron microscope (STEM)2014

    • Author(s)
      Hirohiko Niioka, Tsutomu Araki, Mamoru Hashimoto, et al.
    • Organizer
      UK-Japan workshop on Nanophotonics, Metamaterials and Plasmonics
    • Place of Presentation
      Suita, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] In vivo time-lapse imaging of skin burn wound healing using second-harmonic generation microscopy2014

    • Author(s)
      Takeshi Yasui, Shuichiro Fukushima, Tsutomu Araki, et al.
    • Organizer
      BiOS 2014(Photonic West 2014)
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] 非線形光学マルチモーダル顕微鏡によるアテローム性動脈 硬化症病変の組織学的評価2014

    • Author(s)
      田尾知世,福島修一郎,橋本守,荒木勉
    • Organizer
      第26回バイオエンジニアリング講演会
    • Place of Presentation
      仙台市、宮城
    • Related Report
      2013 Annual Research Report
  • [Presentation] Rare-earth doped Y2O3 nanophosphors for biological cathodeluminescence imaging2013

    • Author(s)
      Hirohiko Niioka, Tsutomu Araki, Mamoru Hashimoto, et al.
    • Organizer
      International Conference on Small Science
    • Place of Presentation
      Las Vegas, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] Fast polarization-resolved SHG microscopy for in vivo imaging of collagen orientation2013

    • Author(s)
      Yuji Tanaka, Shuichiro Fukushima, Tsutomu Araki, et al.
    • Organizer
      CLEO/Pacific Rim 2013
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] Rare-earth doped Y2O3 nanophosphors for biological cathodoluminescence imaging2013

    • Author(s)
      Hirohiko Niioka, TSutomu Araki, Mamoru Hashimoto, et al.
    • Organizer
      International Conference on Small Science
    • Place of Presentation
      Las Vegas, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Cathodoluminescence and scanning transmission electron microscopy for biological imaging2013

    • Author(s)
      Taichi Furukawa, Hirohiko Niioka, Tsutomu Araki, Mamoru Hashimoto, et al.
    • Organizer
      Super imaging 2013
    • Place of Presentation
      Hamamatsu, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] ヒト増殖膜中のコラーゲンと平滑筋様細胞の分布の可視化2013

    • Author(s)
      石原七海, 佐々由季生, 福島修一郎, 荒木勉
    • Organizer
      日本機械学会第24 回バイオフロンティア講演会
    • Place of Presentation
      京都市、京都
    • Related Report
      2013 Annual Research Report
  • [Presentation] 新生血管評価への第二高調波発生顕微鏡の応用2013

    • Author(s)
      永菅大祐,福島修一郎,橋本守,荒木勉
    • Organizer
      日本機械学会第24 回バイオフロンティア講演会
    • Place of Presentation
      京都市、京都
    • Related Report
      2013 Annual Research Report
  • [Presentation] 第二高調波発生顕微鏡によるコラーゲン線維形成過程の観測2013

    • Author(s)
      前原鈴子,福島修一郎,橋本守,荒木勉
    • Organizer
      平成 25 年度日本分光学会国際シンポジウム・年次講演会
    • Place of Presentation
      豊中市、大阪
    • Related Report
      2013 Annual Research Report
  • [Presentation] Detection of lipid uptake by triglyceride deposit cardiomyovasculopathy-indicated fibroblast using CARS microscopy2012

    • Author(s)
      Harsono Cahyadi, Mamoru Hashimoto, Tsutomu Araki, et al.
    • Organizer
      JSAP-OSA Joint Symposia
    • Place of Presentation
      松山市
    • Related Report
      2013 Final Research Report 2012 Annual Research Report
  • [Presentation] Non-staing, in situ visualization of collagen by femtosend laser light and its application to tissue diagnosis2012

    • Author(s)
      Tsutomu Araki
    • Organizer
      The 2nd International Anatomical Sciences and Cell Biology Conference
    • Place of Presentation
      Chiang Mai, Thailand
    • Related Report
      2013 Final Research Report
  • [Presentation] ナノ蛍光体粒子とカソードルミネッセンス顕微鏡を用いたマルチカラー生体イメージング2012

    • Author(s)
      新岡宏彦, 荒木勉, 橋本守, 他
    • Organizer
      日本顕微鏡学会
    • Place of Presentation
      つくば市
    • Related Report
      2013 Final Research Report 2012 Annual Research Report
  • [Presentation] Well-dispersed Nanophosphors for Cathodoluminescence Microscopy Produced by using Laser Ablation Method2012

    • Author(s)
      Taichi Furukawa
    • Organizer
      Focus on Microscopy 2012
    • Place of Presentation
      Singapore
    • Related Report
      2012 Annual Research Report
  • [Presentation] Multicolor cathodoluminescence imaging for biological cells with using nanophosphors2012

    • Author(s)
      Hirohiko Niioka
    • Organizer
      Focus on Microscopy 2012
    • Place of Presentation
      Singapore
    • Related Report
      2012 Annual Research Report
  • [Presentation] Multimodal imaging via light microscopy and cathodoluminescence microscopy for biological specimens with rare-earth doped nanophosphors2012

    • Author(s)
      Taichi Furukawa
    • Organizer
      JSAP-OSA Joint Symposia
    • Place of Presentation
      松山市
    • Related Report
      2012 Annual Research Report
  • [Presentation] Rare-earth Doped Y2O3 Nanophosphors Synthesized for Bio-imaging with Using CL and Fluorescence Microscopy2012

    • Author(s)
      Hirohiko Niioka
    • Organizer
      第8回阪大ナノサイエンス・ナノテクノロジー国際シンポジウム
    • Place of Presentation
      豊中市
    • Related Report
      2012 Annual Research Report
  • [Presentation] Assessment of Arterial Calcification by using X-ray Computed Tomography and Application to Computational Modeling2012

    • Author(s)
      Shingo Hagino
    • Organizer
      The 2nd International Anatomical Sciences and Cell Biology Conference
    • Place of Presentation
      Chiang Mai、タイ
    • Related Report
      2012 Annual Research Report
  • [Presentation] Non-staing, in situ visualization of collagen by femtosend laser light and its application to tissue diagnosis2012

    • Author(s)
      Tsutomu Araki
    • Organizer
      The 2nd International Anatomical Sciences and Cell Biology Conference
    • Place of Presentation
      Chiang Mai、タイ
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 希土類添加ナノ蛍光体粒子を用いた蛍光・CL細胞イメージング2012

    • Author(s)
      新岡宏彦
    • Organizer
      生理研研究会
    • Place of Presentation
      岡崎市
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 高輝度ナノ蛍光体粒子を用いたカソードルミネッセンス細胞イメージング2012

    • Author(s)
      新岡宏彦
    • Organizer
      ナノ学会第10回大会
    • Place of Presentation
      豊中市
    • Related Report
      2012 Annual Research Report
  • [Presentation] コラーゲン線維形成過程における微細構造変化の観測2012

    • Author(s)
      前原 鈴子
    • Organizer
      第24回バイオエンジニアリング講演会
    • Place of Presentation
      豊中市
    • Related Report
      2011 Annual Research Report
  • [Presentation] メカニクスとバイオロジーとフォトニクス2012

    • Author(s)
      荒木 勉
    • Organizer
      第24回バイオエンジニアリング講演会
    • Place of Presentation
      豊中市
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] ナノ蛍光体を用いた多色カソードルミネッセンス細胞イメージング2012

    • Author(s)
      新岡 宏彦
    • Organizer
      日本顕微鏡学会バイオメディカルニューマイクロスコープ分科会 23年度シンポジウム講演会
    • Place of Presentation
      八王子市
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] ナノ蛍光体粒子を用いたカソードルミネッセンス生体イメージング2012

    • Author(s)
      新岡 宏彦
    • Organizer
      第3回デザインバイオニクス講演会
    • Place of Presentation
      豊中市
    • Related Report
      2011 Annual Research Report
  • [Presentation] Skin diagnosis by non-invasive observation of dermal collagen with a second harmonic generation microscope2011

    • Author(s)
      Tsutomu Araki, et al.
    • Organizer
      MAF12
    • Place of Presentation
      Strasbourg, France
    • Related Report
      2013 Final Research Report
  • [Presentation] コラーゲン自己組織化における構造変化の観測2011

    • Author(s)
      前原 鈴子
    • Organizer
      第34回日本バイオレオロジー学会年会
    • Place of Presentation
      吹田市
    • Related Report
      2011 Annual Research Report
  • [Presentation] In vivo observation of skin burn using collagen-sensitive2011

    • Author(s)
      Ryosuke Tanaka
    • Organizer
      Pacific Rim Conf. Lasers and Electro-Optics 2011
    • Place of Presentation
      Sydney(オーストラリア)
    • Related Report
      2011 Annual Research Report
  • [Presentation] カソードルミネッセンスを用いた細胞の超解像イメージング2011

    • Author(s)
      古川 太一
    • Organizer
      第72回応用物理学会学術講演会
    • Place of Presentation
      山形市
    • Related Report
      2011 Annual Research Report
  • [Presentation] Skin diagnosis by non-invasive observation of dermal collagen with a2011

    • Author(s)
      Tsutomu Araki
    • Organizer
      MAF12
    • Place of Presentation
      Strasbourg(フランス)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 偏光分解第2高調波発生顕微鏡を用いたコラーゲン配向状態の定量評価2011

    • Author(s)
      田中 健一郎
    • Organizer
      日本機械学会 第22回バイオフロンティア講演会
    • Place of Presentation
      津市
    • Related Report
      2011 Annual Research Report
  • [Presentation] X線CTを用いた動脈石灰化の定量化2011

    • Author(s)
      萩野 伸悟
    • Organizer
      日本機械学会 第22回バイオフロンティア講演会
    • Place of Presentation
      津市
    • Related Report
      2011 Annual Research Report
  • [Presentation] 電気光学的高速偏光変調を用いた 偏光分解 SHG(第2高調波発生光)顕微鏡2011

    • Author(s)
      田中 佑治
    • Organizer
      Optics & Photonics Japan 2011
    • Place of Presentation
      吹田市
    • Related Report
      2011 Annual Research Report
  • [Presentation] ナノ蛍光体を用いた多色カソードルミネッセンス細胞イメージング2011

    • Author(s)
      新岡 宏彦
    • Organizer
      平成23年度 日本分光学会年次講演会
    • Place of Presentation
      横浜市
    • Related Report
      2011 Annual Research Report
  • [Presentation] Multi-color Cathodoluminescence Imaging for Biological Cells With Using Nanophosphors2011

    • Author(s)
      Hirohiko Niioka
    • Organizer
      ナノサイエンス・ナノテクノロジー国際シンポジウム
    • Place of Presentation
      豊中市
    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://sml.me.es.osaka-u.ac.jp/

    • Related Report
      2013 Final Research Report
  • [Remarks] 荒木研究室ホームページ

    • URL

      http://sml.me.es.osaka-u.ac.jp/Araki_Lab/index.html

    • Related Report
      2013 Annual Research Report
  • [Remarks] 荒木研究室HP

    • URL

      http://sml.me.es.osaka-u.ac.jp/araki_lab/

    • Related Report
      2012 Annual Research Report
  • [Remarks] 荒木研究室HP

    • URL

      http://sml.me.es.osaka-u.ac.jp/araki_lab/

    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] カソードルミネッセンス用標識試薬2012

    • Inventor(s)
      新岡宏彦,橋本守,古川太一
    • Industrial Property Rights Holder
      国立大学法人大阪大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-121380
    • Filing Date
      2012-05-28
    • Related Report
      2013 Final Research Report

URL: 

Published: 2011-04-06   Modified: 2019-07-29  

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