| Budget Amount *help |
¥50,050,000 (Direct Cost: ¥38,500,000、Indirect Cost: ¥11,550,000)
Fiscal Year 2014: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2013: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2012: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥31,590,000 (Direct Cost: ¥24,300,000、Indirect Cost: ¥7,290,000)
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| Outline of Final Research Achievements |
Proper folding and assembling are key processes for biopolymers to exhibit their inherent biological activities. Artificial materials that can manipulate biopolymer folding and asssemling would have variety of applications in biomedical fields. We have designed ionic graft copolymers consisting of a polyion backbone and hydrophilic graft chains to engineer folding and assembling of biopolymers, such as DNA and peptides, having opposite ionic charges. The cationic copolymers formed soluble inter-polyelectrolyte complex with DNA and acidic peptides and enhanced their functions.
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