| Budget Amount *help |
¥47,580,000 (Direct Cost: ¥36,600,000、Indirect Cost: ¥10,980,000)
Fiscal Year 2014: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
Fiscal Year 2013: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
Fiscal Year 2012: ¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2011: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
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| Outline of Final Research Achievements |
The unique behavior of the biomolecules in the carbon nanospace was investigated, and the application for the bio-nanomaterials was attempted. Carbon nano-test-tubes (CNTTs) were obtained from the carbon-coated aluminum anodic oxidized (CAAO) film which has uniform and tubular nanochannels by the removal of the alumina template.
Nucleotide molecules were highly concentrated into the inner nanospace of the CNTTs, and the nucleotide could be released. The observed properties are useful as a nanostorage medium for application of the gene delivery. Fibrillation of the amyloid β peptides (Aβ) which is a cause of Alzheimer disease was inhibited by adding the CNTTs. Redox enzymes immobilized into the carbon nanospace of the CAAO film react with fructose or oxygen and the electrons were directly transported in the CAAO nanochannels. It could be used as an enzymatic electrode. We indeed confirmed that a bio-fuel cell fabricated from the electrodes can work very well.
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