Formation process of self-organized nano-pore arrays on metal substrates and their applications to metallic biomaterials
Project/Area Number |
23246128
|
Research Category |
Grant-in-Aid for Scientific Research (A)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Material processing/treatments
|
Research Institution | Osaka University |
Principal Investigator |
FUJIMOTO SHINJI 大阪大学, 工学(系)研究科(研究院), 教授 (70199371)
|
Co-Investigator(Kenkyū-buntansha) |
TSUCHIYA Hiroaki 大阪大学, 大学院工学研究科, 准教授 (50432513)
MIYABE Sayaka 大阪大学, 大学院工学研究科, 助教 (50584132)
|
Co-Investigator(Renkei-kenkyūsha) |
HIROMOTO Sachiko 独立行政法人物質・材料研究機構 (00343880)
|
Project Period (FY) |
2011-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥47,450,000 (Direct Cost: ¥36,500,000、Indirect Cost: ¥10,950,000)
Fiscal Year 2013: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2012: ¥24,830,000 (Direct Cost: ¥19,100,000、Indirect Cost: ¥5,730,000)
Fiscal Year 2011: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
|
Keywords | ナノホールアレイ / 自己組織化 / 生体材料 / 生体適合性 / 腐食防食 / 電気化学 / 表面機能化 / ステンレス鋼 / 生体親和性 / ナノポーラス / 電気化学プロセス / チタン・チタン合金 / コバルト・クロム合金 |
Research Abstract |
The present work examined the electrochemical formation of self-organized nano-porous structures on metallic biomaterials and evaluates their biocompatibility. Self-organized nano-porous structures were formed on stainless steels, titanium and cobalt-chromium alloy although optimized condition for the pore formation was different depending on the substrates. Cell proliferation was enhanced on porous Type316L stainless steel surfaces compared to a flat stainless steel surface. Repassivation that is one of the most essential factors to suppress metal dissolution induced by deformation was facilitated by the presence of nano-porous structures on stainless steel surface. These findings demonstrated that the formation of self-organized nano-porous structure on stainless steel surface can improve the biocompatibility as well as corrosion resistance during the deformation of stainless steel.
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Report
(4 results)
Research Products
(24 results)