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Activation of catalyzed-liquid phase reactions in a microreactor by acoustic wave resonance oscillation

Research Project

Project/Area Number 23246137
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Catalyst/Resource chemical process
Research InstitutionNagaoka University of Technology

Principal Investigator

INOUE Yasunobu  長岡技術科学大学, 工学部, 特任教授 (30016133)

Co-Investigator(Renkei-kenkyūsha) NISHIYAMA Hiroshi  東京大学, ARPChem柏集中研, 主幹研究員 (50303186)
Project Period (FY) 2011-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥49,400,000 (Direct Cost: ¥38,000,000、Indirect Cost: ¥11,400,000)
Fiscal Year 2013: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2012: ¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2011: ¥23,660,000 (Direct Cost: ¥18,200,000、Indirect Cost: ¥5,460,000)
Keywords触媒・化学プロセス / 表面・界面物性 / マイクロリアクター / 圧電効果 / 共鳴振動 / 固定化酵素 / 液総触媒反応 / 強誘電体 / ガラクトースオキシダーゼ / アミノ酸オキシダーゼ / ミカエリスメンテン定数 / 触媒化学プロセス / 表面界面物性 / 酵素反応 / 液相触媒反応 / 固定化酵素触媒 / 酸触媒
Research Abstract

In aiming at establishing a method for the activation of catalyzed liquid-phase reactions, the acoustic wave resonance oscillation that can be generated on a ferroelectric crystal by rf electric power was applied to the catalytic reactions in a microreactor by the immobilized enzymes. In all the immobilized enzymes such as glucose oxidase, galactose oxidase, D- and L-amino acid oxidase, the remarkable catalytic activity enhancement was induced by the generation of resonance oscillation with considerable decreases in the activation energy of the reactions. The resonance oscillation was revealed to have the significant effects of strengthening the interactions between the enzymes and substrates, and it was concluded that the resonance oscillation is quite useful to activate the immobilized catalysts for liquid phase reactions.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (18 results)

All 2014 2013 2012 2011

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (16 results) (of which Invited: 2 results)

  • [Journal Article] Activation of immobilized glucose oxidase enzyme by acoustic wave resonance oscillation2014

    • Author(s)
      Hiroshi Nishiyama, Masayuki Kazui, Yasunobu Inoue
    • Journal Title

      Chem. Lett.

      Volume: 43 Issue: 5 Pages: 618-620

    • DOI

      10.1246/cl.131218

    • NAID

      130004868127

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of acoustic wave resonance oscillation on immobilized enzyme2014

    • Author(s)
      Hiroshi Nishiyama,Tomoya Watanabe, Yasunobu Inoue
    • Journal Title

      Appl. Surf. Sci.

      Volume: 294 Pages: 66-70

    • DOI

      10.1016/j.apsusc.2013.12.016

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Presentation] 共鳴振動による固定化酵素触媒の活性化の特異性とその機構2013

    • Author(s)
      井上泰宣、西山洋,渡邉智也
    • Organizer
      第112回触媒討論会(A)
    • Place of Presentation
      秋田大学、手形キャンパス
    • Related Report
      2013 Final Research Report
  • [Presentation] Activation of immobilized glucose and galactose oxidase enzymes by acoustic wave resonance oscillation2013

    • Author(s)
      H. Nishiyama, T. Watanabe, Y. Inoue
    • Organizer
      XIth Europian Congr. Catal.
    • Place of Presentation
      Intern. Congr. Center, Lyon, France
    • Related Report
      2013 Final Research Report
  • [Presentation] Immobilized Glucose Oxidase Enzyme by Acoustic Wave Resonance Oscillation2013

    • Author(s)
      Hiroshi Nishiyama, Tomoya Watanabe, Yasunobu Inoue
    • Organizer
      23rd North American Catalysis Society Meeting
    • Place of Presentation
      Galt House, Kentucky, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] Activation of scandium(III) triflate catalyst coordinated on surface for aldol condensation by acoustic wave effects2013

    • Author(s)
      Hiroshi Nishiyama, Ryuusuke Asari, Yasunobu Inoue
    • Organizer
      7th Intern. Symp. Acid-Base Catalysis
    • Place of Presentation
      Garden City Shinagawa, Tokyo
    • Related Report
      2013 Final Research Report
  • [Presentation] 共鳴振動効果による固定化酵素触媒の活性化2013

    • Author(s)
      渡邉智也、数井雅之,西山洋、松原浩、井上泰宣
    • Organizer
      第111回触媒討論会(B)
    • Place of Presentation
      関西大学 千里山キャンパス
    • Related Report
      2013 Final Research Report
  • [Presentation] Acoustic wave excitation of catalysis at surface2013

    • Author(s)
      Yasunobu Inoue
    • Organizer
      Intern. Workshop on Acoustic Activation オブ Surface Processes
    • Place of Presentation
      Breckenridge, Colorado, USA
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Activation of scandium (III) triflate catalyst coordinated on surface for aldol condensation by acoustic wave effects2013

    • Author(s)
      Hiroshi Nishiyama, Ryusuke Asari, Yasunobu Inoue
    • Organizer
      7th International Symposium on Acid-Base Catalysis
    • Place of Presentation
      Garden City Shinagawa, Tokyo, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Immobilized Glucose Oxidase Enzyme by Acoustic Wave Resonance Oscillation2013

    • Author(s)
      Hiroshi Nishiyama, Tomoya Watanabe, Yasunobu Inoue
    • Organizer
      23 rd North American Catalysis Society Meeting
    • Place of Presentation
      Galt House Hotel, Kentucky, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Activation of immobilized glucose and galactose oxidase enzymes by acoustic wave resonance oscillation2013

    • Author(s)
      H. Nishiyama, T. Watanabe, Y. Inoue
    • Organizer
      XIth Europian Congress on Catalysis
    • Place of Presentation
      International Congress Center,Lyon, France
    • Related Report
      2013 Annual Research Report
  • [Presentation] 共鳴振動による固定化酵素触媒の活性化の特異性とその機構2013

    • Author(s)
      井上泰宣・西山洋・渡邉智也
    • Organizer
      第112回触媒学会
    • Place of Presentation
      秋田大学 手形キャンパス
    • Related Report
      2013 Annual Research Report
  • [Presentation] Acoustic wave excitation of catalysis at surfaces2013

    • Author(s)
      (Yasunobu Inoue)
    • Organizer
      International Workshop on Acoustic Activation of Surface Processes
    • Place of Presentation
      Breckenridge, Cololado,USA
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 共鳴振動効果による固定化酵素触媒の活性化2013

    • Author(s)
      渡邉智也、数井雅之、西山洋、松原浩、(井上泰宣)
    • Organizer
      第111回触媒討論会(B)
    • Place of Presentation
      関西大学 千里山キャンパス
    • Related Report
      2012 Annual Research Report
  • [Presentation] マイクロリアクター内でのグルコースオキシダーゼ固定化酵素触媒反応に及ぼす共鳴振動の効果2012

    • Author(s)
      渡邉智也、数井雅之,西山洋、松原浩、井上泰宣
    • Organizer
      第110回触媒討論会(A)
    • Place of Presentation
      九州大学工学部伊都キャンパス
    • Related Report
      2013 Final Research Report
  • [Presentation] マイクロリアクター内でのグルコースオキシダーゼ固定化酵素触媒反応に及ぼす共鳴振動の効果2012

    • Author(s)
      渡邉智也、数井雅之、西山洋、松原浩、(井上泰宣)
    • Organizer
      第110回触媒討論会(A)
    • Place of Presentation
      九州大学工学部伊都キャンパス
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effects of acoustic wave resonance oscillation on catalysis of immobilized glucose oxidase enzyme for glucose oxidation in a microreactor2011

    • Author(s)
      T. Watanabe,M. Kazui,H. Nishiyama, H. Matsubara, Y. Inoue
    • Organizer
      Intern.Symp. Surf.Sci.
    • Place of Presentation
      Tower Hall Funabori Tokyo
    • Year and Date
      2011-12-13
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects of acoustic wave resonance oscillation on catalysis of immobilized glucose oxidase enzyme for glucose oxidation in a microreactor2011

    • Author(s)
      T.Watanabe, M.Kazui, H.Nishiyama, H.Matsubara, Y.Inoue
    • Organizer
      ISSS-6, International Symposium on Surface Science-Toward Nano-, Bio-, and Green Innovation-
    • Place of Presentation
      Tower Hall Funabori, Funabori, Tokyo
    • Year and Date
      2011-12-13
    • Related Report
      2011 Annual Research Report

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Published: 2011-04-06   Modified: 2019-07-29  

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