| Budget Amount *help |
¥49,010,000 (Direct Cost: ¥37,700,000、Indirect Cost: ¥11,310,000)
Fiscal Year 2014: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2013: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2012: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000)
Fiscal Year 2011: ¥21,580,000 (Direct Cost: ¥16,600,000、Indirect Cost: ¥4,980,000)
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| Outline of Final Research Achievements |
Functional properties of diverse rhodopsins were investigated. We found that melanopsins in the zebrafish and lamprey horizontal cells had an ability to elevate intracellular calcium concentration upon light absorption. We also found that melanopsin-expressing horizontal cells connected to visual cells containing rhodopsin, which is basically involved in twilight vision, in the lamprey. In the jumping spider, absorption characteristics of a visual pigment, which is phylogenetically close to melanopsins, contributes to depth perception. In addition, homologs of vertebrate encephalopsins had an ability to decrease intracellular cAMP level via Gi type G protein activation.
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