| Project/Area Number |
23248015
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Toyama Prefectural University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KOMEDA Hidenobu 富山県立大学, 工学部, 准教授 (50285160)
FUHSHUKU Ken-ichi 富山県立大学, 工学部, 助教 (70392090)
SUZUKI Atsuo 名古屋大学, 工学部, 准教授 (40196788)
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| Project Period (FY) |
2011-05-31 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥49,140,000 (Direct Cost: ¥37,800,000、Indirect Cost: ¥11,340,000)
Fiscal Year 2013: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2012: ¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2011: ¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
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| Keywords | 光学分割 / 微生物酵素 / 植物酵素 / ラセマーゼ / 含窒素化合物 / ラセマーセゼ / 含窒素化学物 |
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| Research Abstract |
In this research, we characterized many plant and microbial enzymes acting on nitrogen containing compounds, found in their "Aldoxime-Nitrile Pathways", and utilized them in the synthesis of various useful chemicals. Most of the reactions they catalyze cannot be done in the synthetic chemical reactions. We utilized the following enzymes, such as nitrile hydratases, D- and L-stereospecific amino acid amidases, a-amino-e-aminocaprolactam racemase, plant hydroxynitrile lyases, etc., in the production of useful nitrogen containing compounds.
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