| Budget Amount *help |
¥47,060,000 (Direct Cost: ¥36,200,000、Indirect Cost: ¥10,860,000)
Fiscal Year 2015: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2014: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2013: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2012: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2011: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
|
|---|
| Outline of Final Research Achievements |
Kidney diseases are major national health problems. Various causes including nephritis and diabetes leads to injury in “podocytes” in the kidney, which leads to loss of the whole kidney function. Damage in a subpopulation of podocytes secondarily propagates injury to the neighboring podocytes. In this project, we have established a mouse model in which injury to a fraction of the podocyte population can be induced, analyzed how the podocyte injury spreads and identified several key molecules potentially involved in the propagation of injury. It is expected that drugs targeting these molecules would forestall the progression of kidney diseases.
|
