| Project/Area Number |
23249065
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | Tokyo Denki University |
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Principal Investigator |
HOMMA Akihiko 東京電機大学, 理工学部, 教授 (20287428)
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| Co-Investigator(Kenkyū-buntansha) |
TAENAKA Yoshiyuki 独立行政法人国立循環器病研究センター, 研究所, 副所長 (00142183)
TATSUMI Eisuke 独立行政法人国立循環器病研究センター, 研究所, 部長 (00216996)
TAKEWA Yoshiaki 独立行政法人国立循環器病研究センター, 研究所, 室長 (20332405)
FUKUI Yasuhiro 東京電機大学, 理工学部, 教授 (60112877)
FUNAKUBO Akio 東京電機大学, 理工学部, 教授 (00307670)
OHGOE Yasuharu 東京電機大学, 理工学部, 准教授 (10408643)
NONAKA Kazuhiro 東京電機大学, 理工学部, 准教授 (50584182)
OHNUMA Kentaro 独立行政法人国立循環器病研究センター, 研究所, 流動研究員 (50527992)
SUMIKURA Hirohito 独立行政法人国立循環器病研究センター, 研究所, 流動研究員 (20433998)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥47,840,000 (Direct Cost: ¥36,800,000、Indirect Cost: ¥11,040,000)
Fiscal Year 2013: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2012: ¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
Fiscal Year 2011: ¥20,280,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥4,680,000)
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| Keywords | 全人工心臓 / 補助人工心臓 / ウェアラブル / 駆動装置 / 空気圧駆動式 |
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| Research Abstract |
A pneumatic ventricular assist device (PVAD) and total artificial heart (PTAH) were developed. The size and weight of the driver with the 2 battery are 250x110 x210 mm and 4.3 kg. The performance of the PVAD and PTAH were examined in an overflow type circulation mock and animal tests. The VAD achieved the mean pump flow ranging from 3.4 to 6.7 L/min and the mean electric power consumption ranging from 8.0 to 19.7 W in the circulation mock test. The longest electric discharge of the battery of 7 hours and 38 minutes was possible in the circulation mock. The VAD was also examiend in the chronic animal test using calf. The calf survived for 28 days in good general condition. The bypass flow and the electric power consumption were maintained at 4.1+/-0.4 L/min and 13.3+/-0.4 W. The PTAH using the 2 driver was evaluated in the acute animal test using calf. The mean pump flow ranging from 3.9 to 5.4 L/min and the mean electric power consumption ranging from 5.3 to 17.6 W were achieved.
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