| Budget Amount *help |
¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
Fiscal Year 2014: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2011: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
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| Outline of Final Research Achievements |
In the olfactory bulb, granule cells (GCs) and periglomerular cells (PGs) are 2 major types of GABergic interneurons. Classical studies showed that GCs were anaxonic, whereas PGs have axons extending in the glomerular layer and were considered to play a role in the lateral inhibition. We examined the localization of molecular markers of the axon initial segments on various types of olfactory bulb neurons and found that most of chemically defined subpopulations of PGs were anaxonic. In addition we examined the neurons immunopositive for the newly found calcium-binding protein secretagogin. In the glomerular layer we found some secretagogin positive neurons were a new type of juxtaglomerular neurons, which we named transglomerular cells. We also found that mitral cells and external tufted cells were different in the structural features such as spines of their intraglomerular dendritic tufts.
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