Neural mechanism of flexible cognition and use of symbols: a comparative macaque ECoG and human fMRI study
| Project/Area Number |
23300150
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fusional brain recording science
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKAHARA Kiyoshi 高知工科大学, 総合研究所, 教授 (50372363)
KITAGAWA Junichi 新潟大学, 医歯学系, 准教授 (50373006)
KAWASAKI Keisuke 新潟大学, 医歯学系, 助教 (60511178)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000)
Fiscal Year 2013: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2012: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2011: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
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| Keywords | マカクザル / 前頭葉 / 視覚 / 記号 |
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| Research Abstract |
We developed a visual sign system where object categories were symbolically represented by distinct combinations of visual elements. Macaque monkeys (Macaca fuscata) learned to use these composite symbols by combining and decomposing elements. We conducted multichannel electrtocorticographic (ECoG) recording from the prefrontal cortex and inferior temporal cortex of the monkeys. Analyses of event-related spectral perturbation of the prefrontal ECoG signals revealed areal segregation for combination and decomposition of symbol elements in specific frequency band powers. Functional magnetic resonance imaging in healthy human subjects revealed insular activation during reading particularly when segmentation of letterstrings was required compared to segmentation was not required. Furthermore, we tested symmetry of symbolic use in three macaque monkeys. Symbolic association was symmetrically learned in two macaques but not in one animal, indicating the need for further testing.
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Report
(4 results)
Research Products
(91 results)
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[Journal Article] Alternating zones selective to faces and written words in the human ventral occipitotemporal cortex2013
Author(s)
Matsuo T, Kawasaki K, Kawai K, Majima K, Masuda H, Murakami H, Kunii N, Kamitani Y, Kameyama S, Saito N, Hasegawa I
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Journal Title
Cereb Cortex
Volume: (in press)
Issue: 5
Pages: 1265-77
DOI
Related Report
Peer Reviewed
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[Journal Article] Intrasulcal electrocorticography in macaque monkeys with minimally invasive neurosurgical protocols2011
Author(s)
Matsuo T, Kawasaki K, Osada T, Sawahata H, Suzuki T, Shibata M, Miyakawa N, Nakahara K, Iijima A, Sato N, Kawai K, Saito N, Hasegawa I
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Journal Title
Front Syst Neurosci
Volume: 5
Pages: 34-34
Related Report
Peer Reviewed
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[Journal Article] Intrasulcal electrocorticography in macaque monkeys with minimally invasive neurosurgicalprotocols2011
Author(s)
Matsuo T, Kawasaki K, Osada T, SawahataH, Suzuki T, Shibata M, Miyakawa N, Nakahara K, Iijima A, Sato N, Kawai K, Saito N, Hasegawa I
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Journal Title
Front Syst Neurosci
Volume: 5
Pages: 34-34
DOI
Related Report
Peer Reviewed
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[Presentation] Intrasulcal electrocorticography in macaque monkeys2011
Author(s)
Kawasaki K, Matsuo T, Osada T, Sawahata H, Suzuki T, Shibata M, Miyakawa N, Nakahara K, Sato N, Kawai K, Saito N, Hasegawa I
Organizer
第34回日本神経科学大会
Place of Presentation
パシフィコ横浜(神奈川)
Year and Date
2011-09-17
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[Presentation] 文字の脳内表現と復号化
Author(s)
松尾 健, 間島 慶, 川嵜 圭祐, 川合 謙介, 斉藤 延人, 神谷 之康, 長谷川 功
Organizer
日本脳神経外科学会第71回学術総会
Place of Presentation
大阪
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