| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2014: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2013: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Outline of Final Research Achievements |
A novel process of nanowire formation was developed using metallization of DNA molecules, and electrical property of the fabricated nanowires was evaluated. First, a single DNA molecule was stretched and immobilized between two electrodes in a nanochannel, and a single nanowire was formed by DNA metallization. Next, we demonstrated that our technique permits double-stranded DNA molecules to be specifically metallized while not permitting metallization of single-stranded DNA molecules. Moreover, a novel technique for deoxyribonuclease (DNase) detection was developed using partially-metallized DNA nanowires. Also, we succeeded in extracting plasma from whole blood easily and rapidly using capillary force in a microchannel, and developed a method for detecting specific proteins in the extracted plasma.
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