| Project/Area Number |
23300174
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Biomedical engineering/Biological material science
|
|---|
| Research Institution | National Defense Medical College (2012-2013)
防衛医科大学校 (2011) |
|---|
Principal Investigator |
MORIMOTO YUJI 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 准教授 (10449069)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
NISHIYAMA Nobuhiro 東京工業大学, 資源化学研究所, 教授 (10372385)
KISHIMURA Akihiro 九州大学, 工学(系)研究科(研究院), 准教授 (70422326)
ITO Keiichi 防衛医科大学校, 医学教育部医学科専門課程, 准教授 (90260091)
|
|---|
| Project Period (FY) |
2011-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2013: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2012: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2011: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
|
|---|
| Keywords | 光線力学療法 / ナノメディシン / 標的化診断・治療 / 生体イメージング / 超分子 / トランスレーショナルリサーチ / がん / ドラッグデリバリーシステム / ナノメディスン |
|---|
| Research Abstract |
Enhancing its function and maximizing the accumulation efficiency, we advanced our developed supramolecular drug delivery system (DDS), resulted in the creation of light-activating supramolecular devices. Combining them with state-of-the-art optical technology, we have developed a next-generation theranostic system that can be applied to any sites in the body. Photodynamic therapy using the novel supramolecular DDS-type photosensitizers corresponds to highly selective treatment for tumors, including undetectable micro-lesions without any damage to surrounding normal tissues.
|
