| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2013: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
|
|---|
| Research Abstract |
The functional elaborations including stability in serum medium, cellular uptake, cellular distribution and transcription / translation process are important in the development of the gene vector. Many studies have been performed for these subjects, but there are only a few reports on the promotion of efficiency of a transcription process yet. In this study, we developed the polymeric materials that could exhibit effective a transcription / the translation efficiency and also clarify the mechanism for these materials. Furthermore, we achieved the effective gene expression through the combination of the developed polymeric materials with cationic lipids.
|
