A multi-modal rehabilitation approach that used cartilage stem cell as a subject
| Project/Area Number |
23300199
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kyoto University |
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Principal Investigator |
AOYAMA Tomoki 京都大学, 医学(系)研究科(研究院), 准教授 (90378886)
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| Co-Investigator(Kenkyū-buntansha) |
高桑 徹也 京都大学, 教授 (40244933)
黒木 裕士 京都大学, 教授 (20170110)
三浦 美樹子 島根大学, 助教 (40447925)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2013: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
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| Keywords | リハビリテーション / マルチモダル / 軟骨幹細胞 / 生体内シグナル / 関節軟骨 / 物理療法 / 理学療法 / 運動療法 / 再生医療 / PGE2 |
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| Research Abstract |
In the field of rehabilitation, the analysis was carried out mainly for an individual and the group. It was hard to build the evidence not to adjust to statistics technique, and the compatibility with other domains was poor.
This study aimed for establishment of new multidisciplinary rehabilitation, clarifying the existence of the cartilage stem cell and receptor signalling, when performing excercise. This approach may produce the new aspect of rehabilitation targeting the individual, organ, cell, and molecules.
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Report
(4 results)
Research Products
(62 results)
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[Journal Article] The Transcription Factor Sp3 Regulates the Expression of a Metastasis-Related Marker of Sarcoma, Actin Filament-Associated Protein 1-Like 1 (AFAP1L1).2013
Author(s)
Kajita Y, Kato T Jr, Tamaki S, Furu M, Takahashi R, Nagayama S, Aoyama T, Nishiyama H, Nakamura E, Katagiri T, Nakamura Y, Ogawa O, Toguchida J.
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Journal Title
PLoS One
Volume: 8
Issue: 1
Pages: e49709-e49709
DOI
Related Report
Peer Reviewed
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[Journal Article] Prostaglandin E2 receptor type 2-selective agonist prevents the degeneration of articular cartilage in rabbit knees with traumatic instability2011
Author(s)
Mitsui H, Aoyama T, Furu M, Ito K, Jin Y, Maruyama T, Kanaji T, Fujimura S, Sugihara H, Nishiura A, Otsuka T, Nakamura T, Toguchida J
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Journal Title
Arthritis Res Ther
Volume: 13(5)
NAID
Related Report
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[Journal Article] Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas2011
Author(s)
Furu M, Kajita Y, Nagayama S, Ishibe T, Shima Y, Nishijo K, Uejima D, Takahashi R, Aoyama T, Nakayama T, Nakamura T, Nakashima Y, Ikegawa M, Imoto S, Katagiri T, Nakamura Y, Toguchida J
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Journal Title
Oncogene
Volume: 30(38)
Issue: 38
Pages: 4015-25
DOI
Related Report
Peer Reviewed
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[Presentation] 軟骨細胞に対する長期温熱刺激の安全性と軟骨基質生合成へ与える影響の検討2013
Author(s)
伊藤明良, 青山朋樹, 長井桃子, 山口将希, 飯島弘貴, 太治野純一, 張項凱, 井上大輔, 広瀬太希, 秋山治彦, 黒木裕士
Organizer
第48回日本理学療法学術大会
Place of Presentation
名古屋市
Related Report
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[Presentation] 膝半月板被覆部の軟骨・骨複合体は構造的に脆弱である2013
Author(s)
飯島弘貴, 青山朋樹, 伊藤明良, 太治野純一, 張項凱, 長井桃子, 山口将希, 広瀬太希, 井上大輔, 秋山治彦, 黒木裕士
Organizer
第48回日本理学療法学術大会
Place of Presentation
名古屋市
Related Report
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[Presentation] 寒冷刺激が変形性膝関節症ラットの関節軟骨に及ぼす影響2013
Author(s)
山口将希, 伊藤明良, 長井桃子, 張項凱, 飯島弘貴, 太治野純一, 青山朋樹, 秋山治彦, 広瀬太希, 井上大輔, 黒木裕士
Organizer
第48回日本理学療法学術大会
Place of Presentation
名古屋市
Related Report
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