Effects of a multicomponent activity program to prevent cognitive decline

• Project/Area Number: 23300205
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: National Center for Geriatrics and Gerontology
• Principal Investigator: HIROYUKI Shimada 独立行政法人国立長寿医療研究センター, 老年学・社会科学研究センター 自立支援開発研究部, 室長 (00370974)
• Co-Investigator(Kenkyū-buntansha): 鈴木 隆雄 独立行政法人国立長寿医療研究センター, 研究所, 所長 (30154545) ; 牧迫 飛雄馬 独立行政法人国立長寿医療研究センター, 自立支援システム開発室, 外来研究員 (70510303) ; 土井 剛彦 独立行政法人国立長寿医療研究センター, 自立支援システム開発室, 流動研究員 (60589026)
• Co-Investigator(Renkei-kenkyūsha): 鈴木 隆雄 独立行政法人国立長寿医療研究センター (30154545) ; 牧迫 飛雄馬 独立行政法人国立長寿医療研究センター (70510303) ; 土井 剛彦 独立行政法人国立長寿医療研究センター (60589026)
• Project Period (FY): 2011-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000); Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2012: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2011: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
• Keywords: 軽度認知障害 / 介護予防 / アルツハイマー病 / RCT / 高齢者 / MCI / 認知症 / 予防 / 運動 / 認知的活動 / 介入 / NIRS / 活動 / スクリーニング / 記憶

Research Abstract

The purpose of the study was to identify the effects of a multicomponent activity program (MAP) on cognitive performance in the 159 older adults who had amnestic mild cognitive impairment. The subjects were randomly allocated to the control and the MAP groups. Subjects in the MAP group exercised for 1 d/wk, for a total of 40 times over 10 months. Measurements were analyzed using linear mixed models; analyses assumed missing at random with missingness allowed to be driven by variables included in the analyses. There were significant interactions of group by time on mini-mental state examination (p = .012) and time of moderate physical activity (p < .001) across two groups. These results suggest that exercise improves or supports, at least partly, cognitive performance and physical activity level in older adults with amnestic mild cognitive impairment.

Research Products

• [Journal Article] Olfactory Identification and Cognitive Performance in Community-Dwelling Older Adults With Mild Cognitive Impairment (2014)
  • Author(s): Makizako M, Makizako H, Doi T, Uemura K, Tsutsumimoto K, Miyaguchi H, Shimada H
  • Journal Title: Chemical Senses Volume: 39(1) Pages: 39-46
• [Journal Article] Olfactory Identification and Cognitive Performance in Community-Dwelling Older Adults With Mild Cognitive Impairment. (2014)
  • Author(s): Makizako M, Makizako H, Doi T, Uemura K, Tsutsumimoto K, Miyaguchi H, Shimada H.
  • Journal Title: Chemical Senses Volume: 39 Pages: 39-46
  • Peer Reviewed
• [Journal Article] Factors Associated with Life-Space in Older Adults with Amnestic Mild Cognitive Impairment (2013)
  • Author(s): Uemura K, Shimada H, Makizako H, Yoshida D, Doi T, Yamada M, Suzuki T
  • Journal Title: Geriatr Gerontol Int Volume: 13(1) Pages: 161-6
• [Journal Article] Characteristics of cognitive function in early and late stages of amnestic mild cognitive impairment (2013)
  • Author(s): Doi T, Shimada H, Makizako H, Yoshida D, Shimokata H, Ito K, Washimi Y, Endo H, Suzuki T
  • Journal Title: Geriatr Gerontol Int Volume: 13(1) Pages: 83-9
• [Journal Article] Relationship between dual-task performance and neurocognitive measures in older adults with mild cognitive impairment (2013)
  • Author(s): Makizako H, Doi T, Shimada H, Yoshida D, Takayama Y, Suzuki T
  • Journal Title: Geriatr Gerontol Int Volume: 3(2) Pages: 314-21
• [Journal Article] Relationship between going outdoors daily and activation of the prefrontal cortex during verbal fluency tasks among older adults : a near-infrared spectroscopy study (2013)
  • Author(s): Makizako H, Doi T, Shimada H, Park H, Uemura K, Yoshida D, Tsutsumimoto K, Anan Y, Suzuki T
  • Journal Title: Arch Gerontol Geriatr Volume: 56(1) Pages: 118-23
• [Journal Article] Evaluation of multi-dimensional neurocognitive function using a tablet PC : Test-retest reliability and validity in community-dwelling older adults (2013)
  • Author(s): Makizako H, Shimada H, Park H, Doi T, Yoshida D, Uemura K, Tsutsumimoto K, Suzuki T
  • Journal Title: Geriatr Gerontol Int Volume: 13(4) Pages: 860-6
• [Journal Article] Gait adaptability and brain activity during unaccustomed treadmill walking in healthy elderly females (2013)
  • Author(s): Shimada H, Ishii K, Ishiwata K, Oda K, Suzukawa M, Makizako H, Doi T, Suzuki T
  • Journal Title: Gait Posture Volume: 38(2) Pages: 203-8
• [Journal Article] Cognitive Function Affects Trainability for Physical Performance in Exercise Intervention among Older Adults with Mild Cognitive Impairment (2013)
  • Author(s): Uemura K, Shimada H, Makizako H, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Suzuki T
  • Journal Title: Clinical Interventions in Aging Volume: 8 Pages: 97-102
• [Journal Article] Combined Prevalence of Frailty and Mild Cognitive Impairment in a Population of Elderly Japanese People (2013)
  • Author(s): Shimada H, Makizako H, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Uemura K, Ito T, Lee S, Park H, Suzuki T
  • Journal Title: JAMDA Volume: 14(7) Pages: 518-524
• [Journal Article] A randomized controlled trial of multicomponent exercise in older adults with mild cognitive impairment (2013)
  • Author(s): Suzuki T, Shimada H, Makizako H, Doi T, Yoshida D, Ito K, Shimokata H, Washimi Y, Endo H, Kato T
  • Journal Title: PLoS One Volume: 8(4)
• [Journal Article] Poor balance and lower gray matter volume predict falls in older adults with mild cognitive impairment (2013)
  • Author(s): Makizako H, Shimada H, Doi T, Hyuntae Park, Yoshida D, Uemura K, Tsutsumimoto K, Liu-Ambrose T, Suzuki T
  • Journal Title: BMC Neurology Volume: 13(1) Pages: 102-102
• [Journal Article] Six-Minute Walking Distance Correlated with Memory and Brain Volume in Older Adults with Mild Cognitive Impairment : A Voxel-Based Morphometry Study (2013)
  • Author(s): Makizako H, Shimada H, Doi T, Park H, Yoshida D, Suzuki T
  • Journal Title: Dement Geriatr Cogn Disord Extra Volume: 3 Pages: 223-232
• [Journal Article] Evaluation of multidimensional neurocognitive function using a tablet personal computer : Test-retest reliability and validity in community-dwelling older adults (2013)
  • Author(s): Makizako H, Shimada H, Park H, Doi T, Yoshida D, Uemura K, Tsutsumimoto K, Suzuki T
  • Journal Title: Geriatr Gerontol Int Volume: 13 Pages: 860-865
• [Journal Article] Cognitive Activities and Instrumental Activity of Daily Living in Older Adults with Mild Cognitive Impairment (2013)
  • Author(s): Doi T, Shimada H, Makizako H, Lee S, Park H, Tsutsumimoto K, Uemura K, Yoshida D, Anan Y, Suzuki T
  • Journal Title: Dement Geriatr Cogn Disord Extra Volume: 3 Pages: 398-406
• [Journal Article] Age-related differences in the influence of cognitive task performance on postural control under unstable balance conditions (2013)
  • Author(s): Makizako H, Furuna T, Ihira H, Shimada H
  • Journal Title: International Journal of Gerontology Volume: 7 Pages: 199-204
• [Journal Article] 認知症の危険因子と予防に関するエビデンス (2013)
  • Author(s): 島田裕之
  • Journal Title: 公衆衛生 Volume: 77(8) Pages: 675-677
• [Journal Article] 高齢者における健康増進Seminar 9. 認知症予防と健康増進 (2013)
  • Author(s): 島田裕之
  • Journal Title: 老年医学 Volume: 51(9) Pages: 941-945
• [Journal Article] Factors Associated with Life-Space in Older Adults with Amnestic Mild Cognitive Impairment. (2013)
  • Author(s): Uemura K, Shimada H, Makizako H, Yoshida D, Doi T, Yamada M, Suzuki T.
  • Journal Title: Geriatr Gerontol Int Volume: 13 Pages: 161-166
  • Peer Reviewed
• [Journal Article] Characteristics of cognitive function in early and late stages of amnestic mild cognitive impairment. (2013)
  • Author(s): Doi T, Shimada H, Makizako H, Yoshida D, Shimokata H, Ito K, Washimi Y, Endo H, Suzuki T.
  • Journal Title: Geriatr Gerontol Int Volume: 13 Pages: 83-89
  • Peer Reviewed
• [Journal Article] Relationship between dual-task performance and neurocognitive measures in older adults with mild cognitive impairment. (2013)
  • Author(s): Makizako H, Doi T, Shimada H, Yoshida D, Takayama Y, Suzuki T.
  • Journal Title: Geriatr Gerontol Int Volume: 13 Pages: 314-321
  • Peer Reviewed
• [Journal Article] Relationship between going outdoors daily and activation of the prefrontal cortex during verbal fluency tasks among older adults: a near-infrared spectroscopy study. (2013)
  • Author(s): Makizako H, Doi T, Shimada H, Park H, Uemura K, Yoshida D, Tsutsumimoto K, Anan Y, Suzuki T.
  • Journal Title: Arch Gerontol Geriatr Volume: 56 Pages: 118-123
  • Peer Reviewed
• [Journal Article] Evaluation of multi-dimensional neurocognitive function using a tablet PC: Test-retest reliability and validity in community-dwelling older adults. (2013)
  • Author(s): Makizako H, Shimada H, Park H, Doi T, Yoshida D, Uemura K, Tsutsumimoto K, Suzuki T.
  • Journal Title: Geriatr Gerontol Int Volume: 13 Pages: 860-866
  • Peer Reviewed
• [Journal Article] Gait adaptability and brain activity during unaccustomed treadmill walking in healthy elderly females. (2013)
  • Author(s): Shimada H, Ishii K, Ishiwata K, Oda K, Suzukawa M, Makizako H, Doi T, Suzuki T.
  • Journal Title: Gait Posture Volume: 38 Pages: 203-208
  • Peer Reviewed
• [Journal Article] Cognitive Function Affects Trainability for Physical Performance in Exercise Intervention among Older Adults with Mild Cognitive Impairment. (2013)
  • Author(s): Uemura K, Shimada H, Makizako H, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Suzuki T.
  • Journal Title: Clinical Interventions in Aging Volume: 8 Pages: 97-102
  • Peer Reviewed
• [Journal Article] Combined Prevalence of Frailty and Mild Cognitive Impairment in a Population of Elderly Japanese People. (2013)
  • Author(s): Shimada H, Makizako H, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Uemura K, Ito T, Lee S, Park H, Suzuki T.
  • Journal Title: JAMDA Volume: 14 Pages: 518-524
  • Peer Reviewed
• [Journal Article] A randomized controlled trial of multicomponent exercise in older adults with mild cognitive impairment. (2013)
  • Author(s): Suzuki T, Shimada H, Makizako H, Doi T, Yoshida D, Ito K, Shimokata H, Washimi Y, Endo H, Kato T.
  • Journal Title: PLoS One Volume: 8
  • Peer Reviewed
• [Journal Article] Poor balance and lower gray matter volume predict falls in older adults with mild cognitive impairment. (2013)
  • Author(s): Makizako H, Shimada H, Doi T, Hyuntae Park, Yoshida D, Uemura K, Tsutsumimoto K, Liu-Ambrose T, Suzuki T.
  • Journal Title: BMC Neurology Volume: 13 Pages: 102-102
  • Peer Reviewed
• [Journal Article] Six-Minute Walking Distance Correlated with Memory and Brain Volume in Older Adults with Mild Cognitive Impairment: A Voxel-Based Morphometry Study. (2013)
  • Author(s): Makizako H, Shimada H, Doi T, Park H, Yoshida D, Suzuki T.
  • Journal Title: Dement Geriatr Cogn Disord Extra Volume: 3 Pages: 223-232
  • Peer Reviewed
• [Journal Article] Evaluation of multidimensional neurocognitive function using a tablet personal computer: Test–retest reliability and validity in community-dwelling older adults. (2013)
  • Author(s): Makizako H, Shimada H, Park H, Doi T, Yoshida D, Uemura K, Tsutsumimoto K, Suzuki T.
  • Journal Title: Geriatr Gerontol Int Volume: 13 Pages: 860-866
  • Peer Reviewed
• [Journal Article] Cognitive Activities and Instrumental Activity of Daily Living in Older Adults with Mild Cognitive Impairment. (2013)
  • Author(s): Doi T, Shimada H, Makizako H, Lee S, Park H, Tsutsumimoto K, Uemura K, Yoshida D, Anan Y, Suzuki T.
  • Journal Title: Dement Geriatr Cogn Disord Extra Volume: 3 Pages: 398-406
  • Peer Reviewed
• [Journal Article] Age-related differences in the influence of cognitive task performance on postural control under unstable balance conditions. (2013)
  • Author(s): Makizako H, Furuna T, Ihira H, Shimada H.
  • Journal Title: International Journal of Gerontology Volume: 7 Pages: 199-204
  • Peer Reviewed
• [Journal Article] 認知症の危険因子と予防に関するエビデンス. (2013)
  • Author(s): 島田裕之
  • Journal Title: 公衆衛生 Volume: 77 Pages: 675-677
• [Journal Article] 高齢者における健康増進 (2013)
  • Author(s): 島田裕之
  • Journal Title: 老年医学 Volume: 51 Pages: 941-945
• [Journal Article] Effects of multicomponent exercise on spatial-temporal gait parameters among the elderly with amnestic mild cognitive impairment : Preliminary results from a randomized controlled trial. (2013)
  • Author(s): Doi T, Makizako H, Shimada H, Yoshida D, Tsutsumimoto K, Sawa R, Misu S, Suzuki T.
  • Journal Title: Archives of Gerontology and Geriatrics Volume: 56 Issue: 1 Pages: 104-108
  • DOI: 10.1016/j.archger.2012.09.003
  • Peer Reviewed
• [Journal Article] Effects of multicomponent exercise on cognitive function in older adults with amnestic mild cognitive impairment : A randomized controlled trial. (2013)
  • Author(s): Suzuki T, Shimada H, Makizako H, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Uemura K, Lee S, Park H.
  • Journal Title: BMC Neurology Volume: 12 Issue: 1 Pages: 128-128
  • DOI: 10.1186/1471-2377-12-128
  • Peer Reviewed
• [Journal Article] Relationship between Atrophy of the Medial Temporal Areas and Memory Function in Elderly Adults (2012)
  • Author(s): Shimada H, Kato T, Ito K, Makizako H, Doi T, Yoshida D, Shimokata H, Washimi Y, Endo T, Suzuki T
  • Journal Title: Eur Neurol Volume: 67(3) Pages: 168-177
• [Journal Article] Brain Atrophy and Trunk Stability during Dual-task Walking among Older Adults (2012)
  • Author(s): Doi T, Makizako H, Shimada H, Yoshida D, Ito K, Kato T, Ando H, Suzuki T
  • Journal Title: J Gerontol Volume: 67(7) Pages: 790-5
• [Journal Article] Imaging of glucose uptake during walking in elderly adults (2012)
  • Author(s): Shimada H
  • Journal Title: Curr Aging Sci Volume: 5(1) Pages: 51-57
• [Journal Article] よくわかる研究法25研究への私の取り組み : 大規模スクリーニング調査実施の経験を交えて (2012)
  • Author(s): 島田裕之
  • Journal Title: 理学療法 Volume: 29(3) Pages: 329-335
• [Journal Article] 日本における認知症の現在と今後の動向 (2012)
  • Author(s): 島田裕之, 吉田大輔
  • Journal Title: 訪問リハビリテーション Volume: 1(5) Pages: 309-313
• [Journal Article] Effects of Exercise Intervention on Vascular Risk Factors in Older Adults with Mild Cognitive Impairment : a Randomized Controlled Trial (2012)
  • Author(s): Uemura K, Doi T, Shimada H, Makizako H, Yoshida D, Tsutsumimoto K, Anan Y, Suzuki T
  • Journal Title: Dementia and Geriatric Cognitive Disorders Extra Volume: 2(1) Pages: 445-55
• [Journal Article] Effects of multicomponent exercise on spatial-temporal gait parametersamong the elderly with amnestic mild cognitive impairment : Preliminary results from a randomized controlled trial (2012)
  • Author(s): Doi T, Makizako H, Shimada H, Yoshida D, Tsutsumimoto K, Sawa R, Misu S, Suzuki T
  • Journal Title: Arch Gerontol Geriatr Volume: 56(1) Pages: 104-8
• [Journal Article] Effects of Multicomponent Exercise on cognitive Function in Older Adults with Amnestic Mild Cognitive Impairment : A Randomized Controlled Trial (2012)
  • Author(s): Suzuki T, Shimada H, Makizako H, Doi T, Yosida D, Tsutsumimoto K, Anan Y, Uemura K, Lee S, Park H
  • Journal Title: BMC Neurol Volume: 12 Pages: 128-128
• [Journal Article] Does a multicomponent exercise program improve dual-task performance in amnestic and cognitive impairment? A randomized controlled trial (2012)
  • Author(s): Makizako H, Doi T, Shimada H, Yoshida D, Tsutsumimoto K, Uemura K, Suzuki T
  • Journal Title: Aging Clin Exp Res Volume: 24(6) Pages: 640-6
• [Journal Article] 高齢者の認知機能の評価と測定 (2012)
  • Author(s): 牧迫飛雄馬. 島田裕之
  • Journal Title: 体育の科学 Volume: 62(7) Pages: 485-490
• [Journal Article] Effects of exercise intervention on vascular risk factors in older adults with mild cognitive impairment : a randomized controlled trial (2012)
  • Author(s): Kazuki Uemura
  • Journal Title: Dementia & Geriatric Cognitivc Disorder Extra Volume: 2 Issue: 1 Pages: 445-455
  • DOI: 10.1159/000343486
  • Peer Reviewed
• [Journal Article] Does a multicomponent exercise program improve dual-task performance in amnestic and cognitive impairment? A randomized controlled trial. (2012)
  • Author(s): Makizako H
  • Journal Title: Aging Clin Exp Res Volume: 24 Pages: 640-646
  • Peer Reviewed
• [Journal Article] Relationship between Atrophy of the Medial Temporal Areas and Memory Function in Elderly Adults (2012)
  • Author(s): Shimada H, et al
  • Journal Title: Eur Neurol Volume: 67 Pages: 168-177
  • Peer Reviewed
• [Journal Article] The association between decline in physical functioning and atrophy of medial temporal areas in community-dwelling older adults with amnestic and non-amnestic mild cognitive impairment (2011)
  • Author(s): Makizako H, Shimada H, Doi T, Yoshida D, Ito K, Kato T, Shimokata H, Washimi Y, Endo H, Suzuki T.
  • Journal Title: Arch Phys Med Rehabil Volume: 92(12) Pages: 1992-9
• [Journal Article] Dual-task costs for whole trunk movement during gait (2011)
  • Author(s): Doi T, Asai T, Hirata S, Ando H
  • Journal Title: Gait Posture Volume: 33(4) Pages: 712-714
• [Journal Article] 介護予防の新たな方向性 : 認知機能低下予防の効果 (2011)
  • Author(s): 島田裕之, 牧迫飛雄馬, 吉田大輔, 土井剛彦, 堤本広大, 阿南祐也
  • Journal Title: 地域リハビリテーション Volume: 6(12) Pages: 928-932
  • NAID: 40019131282
• [Journal Article] 高齢者の脳機能と運動 アルツハイマー病予防に対する運動の効果 (2011)
  • Author(s): 島田裕之, 朴眩泰
  • Journal Title: 体育の科学 Volume: 62(3) Pages: 200-208
• [Journal Article] 認知症予防 : 運動療法 (2011)
  • Author(s): 鈴木隆雄, 島田裕之
  • Journal Title: 医学のあゆみ Volume: 239(5) Pages: 392-399
• [Journal Article] The association between decline in physical functioning and atrophy of medial temporal areas in community-dwelling older adults with amnestic and non-amnestic mild cognitive impairment (2011)
  • Author(s): Makizako H, Shimada H, et al
  • Journal Title: Arch Phys Med Rehabil Volume: 92 Pages: 1992-1999
  • Peer Reviewed
• [Journal Article] 介護予防の新たな方向性:認知機能低下予防の効果 (2011)
  • Author(s): 島田裕之, 他
  • Journal Title: 地域リハビリテーション Volume: 6 Pages: 10-16
  • NAID: 40019131282
• [Journal Article] Brain Atrophy and Trunk Stability during Dual-task Walking among Older Adults
  • Author(s): Doi T, Shimada H, et al
  • Journal Title: J Gerontol Volume: (In press)
  • Peer Reviewed
• [Journal Article] The relationship between atrophy of the medial temporal area and daily activities in older adults with mild cognitive impairment
  • Author(s): Yoshida D, Shimada H, et al
  • Journal Title: Aging Clinical and Experimental Research Volume: (In press)
  • Peer Reviewed
• [Presentation] Non-pharmacological therapy for MCI : a RCT of exercise and cognitive stimulation (2013)
  • Author(s): Shimada H
  • Organizer: The 20th IAGG World Congress of Gerontology and Geriatrics
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2013-06-25
• [Presentation] Intervention trial for prevention of cognitive decline among the community elderly in japan (2013)
  • Author(s): Suzuki T, Yoshida D, Makizako H, Park H, Lee S, Shimada H
  • Organizer: The 20th IAGG World Congress of Gerontology and Geriatrics
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2013-06-25
• [Presentation] Apolipoprotein E and Physical Function among Older People with Mild Cognitive Impairment (2013)
  • Author(s): Doi T, Shimada H, Makizako H, Park H, Lee S, Tsutsumimoto K, Uemura K, Yoshida D, Anan Y, Ito T, Suzuki T
  • Organizer: The 20th IAGG World Congress of Gerontology and Geriatrics
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2013-06-25
• [Presentation] 軽度認知障害を有する高齢者における睡眠と日常身体活動との関連 (2013)
  • Author(s): 朴眩泰, 島田裕之, 牧迫飛雄馬, 土井剛彦, 堤本広大, 上村一貴, 李相侖, 吉田大輔, 阿南祐也, 伊藤忠, 鈴木隆雄
  • Organizer: 第48回日本理学療法学術大会
  • Place of Presentation: 名古屋
  • Year and Date: 2013-05-26
• [Presentation] 軽度認知障害を有する高齢者におけるdual-task歩行能力と前頭前野内の灰白質 (2013)
  • Author(s): 土井剛彦, 牧迫飛雄馬, 島田裕之, 堤本広大, 上村一貴, 朴眩泰, 李相侖, 吉田大輔, 阿南祐也, 伊藤忠, 鈴木隆雄
  • Organizer: 第48回日本理学療法学術大会
  • Place of Presentation: 名古屋
  • Year and Date: 2013-05-24
• [Presentation] 軽度認知障害を有する高齢者を対象とした社会活動の検討 (2013)
  • Author(s): 李相侖, 島田裕之, 朴眩泰, 牧迫飛雄馬, 土井剛彦, 堤本広大, 上村一貴, 吉田大輔, 阿南祐也, 伊藤忠, 鈴木隆雄
  • Organizer: 第48回日本理学療法学術大会
  • Place of Presentation: 名古屋
  • Year and Date: 2013-05-24
• [Presentation] Gait Ability and Congnitive Function Among Older Adults With Mild Cognitive Impairments (2013)
  • Author(s): Doi T, Shimada H, Makizako H, Tsutsumimoto K, Uemura K, Anan Y, Nakakubo S, Suzuki T
  • Organizer: Alzheimer's Association International Conference 2013
  • Place of Presentation: Boston, USA
• [Presentation] Non-pharmacological therapy for MCI: a RCT of exercise and cognitive stimulation. (2013)
  • Author(s): Shimada H.
  • Organizer: The 20th IAGG World Congress of Gerontology and Geriatrics
  • Place of Presentation: Seoul, South Korea
  • Invited
• [Presentation] Intervention trial for prevention of cognitive decline among the community elderly in japan. (2013)
  • Author(s): Suzuki T, Yoshida D, Makizako H, Park H, Lee S, Shimada H.
  • Organizer: The 20th IAGG World Congress of Gerontology and Geriatrics
  • Place of Presentation: Seoul, South Korea
• [Presentation] Cognitive Activities and Instrumental Activity of Daily Living among Older People with Mild Cognitive Impairment. (2013)
  • Author(s): Doi T
  • Organizer: 11th International Conference on Alzheimer's and Parkinson's Diseases
  • Place of Presentation: Florence, Italy
• [Presentation] Does a multicomponent exercise program improve dual-task performance in amnestic mild cognitive impairment? A randomized controlled trial (2012)
  • Author(s): Makizako H, Doi T, Shimada H, Yoshida D, Tsutsumimoto K, Uemura K, Suzuki T
  • Organizer: Alzheimer's Association International Conference 2012
  • Place of Presentation: Vancouver, Canada
  • Year and Date: 2012-07-17
• [Presentation] Effects of Multicomponent Exercise on Cognitive Function in the Older Adults with Amnestic Mild Cognitive Impairment : A Randomized Control Trial (2012)
  • Author(s): Shimada H, Suzuki T, Makizako H, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Uemura K, Park H
  • Organizer: Alzheimer's Association International Conference 2012
  • Place of Presentation: Vancouver, Canada
  • Year and Date: 2012-07-15
• [Presentation] 多面的運動介入が軽度認知症高齢者の脳活動に及ぼす影響 (2012)
  • Author(s): 朴眩泰, 島田裕之, 牧迫飛雄馬, 土井剛彦, 吉田大輔, 堤本広大, 上村一貴, 阿南祐也, 鈴木隆雄
  • Organizer: 第54回日本老年医学会学術集会
  • Place of Presentation: 東京
  • Year and Date: 2012-06-29
• [Presentation] 地域高齢者における転倒と運動機能との関連-認知機能の影響- (2012)
  • Author(s): 牧迫飛雄馬, 島田裕之, 吉田大輔, 土井剛彦, 堤本広大, 阿南祐也, 上村一貴, 朴眩泰, 鈴木隆雄
  • Organizer: 第54回日本老年医学会学術集会
  • Place of Presentation: 東京
  • Year and Date: 2012-06-28
• [Presentation] 高齢者における外出頻度は文字流暢性課題中の脳血流動態に影響するか? (2012)
  • Author(s): 牧迫飛雄馬, 島田裕之, 土井剛彦, 吉田大輔, 堤本広大, 上村一貴, 阿南祐也, 大矢敏久, 朴眩泰, 鈴木隆雄
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
  • Year and Date: 2012-05-27
• [Presentation] 軽度認知障害を有する高齢者に対する運動による認知機能低下抑制. -ランダム化比較試験による検討- (2012)
  • Author(s): 島田裕之, 牧迫飛雄馬, 土井剛彦, 吉田大輔, 堤本広大, 上村一貴, 阿南祐也, 大矢敏久, 鈴木隆雄
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
  • Year and Date: 2012-05-27
• [Presentation] 軽度認知障害高齢者に対する多面的運動介入が脳活動に与える影響 : 近赤外分光法による脳活性の計測 (2012)
  • Author(s): 朴眩泰, 島田裕之, 土井剛彦, 牧迫飛雄馬, 吉田大輔, 堤本広大, 上村一貴, 阿南祐也, 大矢敏久, 鈴木隆雄
  • Organizer: 47回日本理学療法学術大会
  • Place of Presentation: 神戸
  • Year and Date: 2012-05-27
• [Presentation] 軽度認知障害を有する高齢者における身体活動と運動機能および認知機能の関係 (2012)
  • Author(s): 阿南祐也, 島田裕之, 朴眩泰, 牧迫飛雄馬, 土井剛彦, 吉田大輔, 堤本広大, 上村一貴, 大矢敏久, 鈴木隆雄
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
  • Year and Date: 2012-05-27
• [Presentation] 軽度認知障害を有する高齢者に対する運動介入によるTimed Up & Go Test の向上には認知機能が影響する (2012)
  • Author(s): 上村一貴, 島田裕之, 牧迫飛雄馬, 土井剛彦, 吉田大輔, 堤本広大, 朴眩泰, 阿南祐也, 大矢敏久, 内山靖
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
  • Year and Date: 2012-05-27
• [Presentation] 複合的運動プログラムは健忘型軽度認知障害を有する高齢者の二重課題遂行能力の改善に効果があるか? -ランダム化比較試験による検討- (2012)
  • Author(s): 牧迫飛雄馬, 島田裕之, 土井剛彦, 吉田大輔, 堤本広大, 上村一貴, 阿南祐也, 大矢敏久, 鈴木隆雄
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
  • Year and Date: 2012-05-26
• [Presentation] 軽度認知障害高齢者に対する複合的運動プログラムは歩行能力を改善できるのか? -ランダム化比較試験による検証- (2012)
  • Author(s): 土井剛彦, 牧迫飛雄馬, 島田裕之, 吉田大輔, 堤本広大, 上村一貴, 澤龍一, 朴眩泰, 阿南祐也, 大矢敏久, 鈴木隆雄
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
  • Year and Date: 2012-05-26
• [Presentation] 軽度認知機能障害を有する高齢者における認知機能向上の規定因子 (2012)
  • Author(s): 島田裕之, 牧迫飛雄馬, 土井剛彦, 吉田大輔, 提本広大, 上村一貴, 阿南祐也, 大矢敏久, 朴眩泰, 鈴木隆雄
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
  • Year and Date: 2012-05-25
• [Presentation] The effects of multicomponent exercise on gait performance among older adults with mild cognitive impairment : a randomized controlled trial (2012)
  • Author(s): Doi T, Makizako H, Shimada H, Yoshida D, Tsutsumimoto K, Sawa R, Anan Y, Uemura K, Suzuki T
  • Organizer: Joint World Congress of International Society for Posture and Gait Research and Gait & Mental Function
  • Place of Presentation: Trondheim, Norway
• [Presentation] Effects of Multicomponent Exercise on Cognitive Function in the Older Adults with Amnestic Mild Cognitive Impairment: A Randomized Control Trial. (2012)
  • Author(s): Shimada H
  • Organizer: Alzheimer's Association International Conference 2012
  • Place of Presentation: Vancouver, Canada
• [Presentation] Does a multicomponent exercise program improve dual-task performance in amnestic mild cognitive impairment? A randomized controlled trial. (2012)
  • Author(s): Makizako H
  • Organizer: Alzheimer’s Association International Conference 2012
  • Place of Presentation: Vancouver, Canada
• [Presentation] The impact of exhaustion on gait smoothness among Japanese older people. (2012)
  • Author(s): Tsutsumimoto K
  • Organizer: Joint World Congress of International Society for Posture and Gait Research and Gait & Mental Function
  • Place of Presentation: Trondheim, Norway
• [Presentation] The effects of multicomponent exercise on gait performance among older adults with mild cognitive impairment: a randomized controlled trial. (2012)
  • Author(s): Doi T
  • Organizer: Joint World Congress of International Society for Posture and Gait Research and Gait & Mental Function
  • Place of Presentation: Trondheim, Norway
• [Presentation] 軽度認知障害を有する高齢者の運動機能低下および脳萎縮と将来の転倒発生との関連. (2012)
  • Author(s): 牧迫飛雄馬
  • Organizer: 第9回転倒予防医学研究会研究集会
  • Place of Presentation: 東京
• [Presentation] 多面的運動介入が軽度認知症高齢者の脳活動に及ぼす影響. (2012)
  • Author(s): 朴眩泰
  • Organizer: 第54回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 要支援・要介護認定と身体機能. (2012)
  • Author(s): 島田裕之
  • Organizer: 第54回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 地域高齢者における転倒と運動機能との関連－認知機能の影響－. (2012)
  • Author(s): 牧迫飛雄馬
  • Organizer: 第54回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 3ヶ月間の機能的トレーニングが85歳以上の要支援高齢者の身体機能に及ぼす効果. (2012)
  • Author(s): 橋立博幸
  • Organizer: 第54回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 要介護高齢者の運動機能と運動FIMとの関連. (2012)
  • Author(s): 林悠太
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 要介護高齢者の認知機能低下の特徴―10,865名に対するFIMの大規模調査―. (2012)
  • Author(s): 鈴川芽久美
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 活力低下（exhaustion）を有する高齢者における歩行の質的変化. (2012)
  • Author(s): 堤本広大
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 様々な環境条件下での移乗動作自立に影響を与える因子. (2012)
  • Author(s): 石本麻友子
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 軽度認知障害を有する高齢者に対する運動介入によるTimed Up & Go Testの向上には認知機能が影響する. (2012)
  • Author(s): 上村一貴
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 高齢者における外出頻度は文字流暢性課題中の脳血流動態に影響するか？ (2012)
  • Author(s): 牧迫飛雄馬
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 軽度認知障害を有する高齢者に対する運動による認知機能低下抑制―ランダム化比較試験による検討―. (2012)
  • Author(s): 島田裕之
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 軽度認知障害高齢者に対する多面的運動介入が脳活動に与える影響：近赤外分光法による脳活性の計測. (2012)
  • Author(s): 朴眩泰
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 肥満を伴ったサルコペニアは歩行機能と強く関連するか. (2012)
  • Author(s): 吉田大輔
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 軽度認知障害を有する高齢者における身体活動と運動機能および認知機能の関係. (2012)
  • Author(s): 阿南祐也
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 軽度認知障害高齢者に対する複合的運動プログラムは歩行能力を改善できるのか？―ランダム化比較試験による検証―. (2012)
  • Author(s): 土井剛彦
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 複合的運動プログラムは健忘型軽度認知障害を有する高齢者の二重課題遂行能力の改善に効果があるか？―ランダム化比較試験による検討―. (2012)
  • Author(s): 牧迫飛雄馬
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 生活環境支援を考える上でのエビデンスと活動—ここまで解っている・ここまで取り組んでいる―認知機能低下予防のエビデンス～認知症予防を目指して～. (2012)
  • Author(s): 島田裕之
  • Organizer: 第47回日本理学療法学術大会, 生活環境支援シンポジウム
  • Place of Presentation: 神戸
• [Presentation] 軽度認知機能障害を有する高齢者における認知機能向上の規定因子. (2012)
  • Author(s): 島田裕之
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 要支援者と要介護者間の心身機能の比較. (2012)
  • Author(s): 波戸真之介
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] 地域在住高齢者における皮下脂肪厚・筋厚と近赤外光吸光度との関連について. (2012)
  • Author(s): 吉松竜貴
  • Organizer: 第47回日本理学療法学術大会
  • Place of Presentation: 神戸
• [Presentation] The effect of exercise on regional brain glucose metabolism in elderly adults : a randomized control trial (2011)
  • Author(s): Shimada H, Ishii K, Suzukawa M, Ishiwata K, Oda K, Makizako H, Doi T, Yoshida D, Suzuki T
  • Organizer: Alzheimer's Association International Conference
  • Place of Presentation: Paris
  • Year and Date: 2011-07-19
• [Presentation] Dual-task performance and multi-domain of neurocognitive functions in older adults with and without amnestic mild cognitive impairment (2011)
  • Author(s): Makizako H, Shimada H, Suzuki T, Doi T, Yoshida D, Shimokata H, Ito K, Washimi Y, Endo H
  • Organizer: Alzheimer's Association International Conference
  • Place of Presentation: Paris
  • Year and Date: 2011-07-19
• [Presentation] Whole Brain Atrophy and Spatiotemporal Gait Parameters during Dual-task Gait (2011)
  • Author(s): Doi T, Shimada H, Makizako H, Yoshida D, Shimokata H, Ito K, Washimi Y, Endo H, Suzuki T
  • Organizer: Alzheimer's Association International Conference
  • Place of Presentation: Paris
  • Year and Date: 2011-07-19
• [Presentation] The relationship between atrophy of the medial temporal area and daily activities in community-dwelling older adults (2011)
  • Author(s): Yoshida D, Shimada H, Makizako H, Doi T, Ito K, Kato T, Shimokata H, Washimi Y, Endo H, Suzuki T
  • Organizer: Alzheimer's Association International Conference
  • Place of Presentation: Paris
  • Year and Date: 2011-07-19
• [Presentation] The effect of exercise on regional brain glucose metabolism in elderly adults : arandomized control trial (2011)
  • Author(s): Shimada H, et al
  • Organizer: Alzheimer's Association International Conference
  • Place of Presentation: Paris
  • Year and Date: 2011-07-19
• [Presentation] Aerobic capacity is related to entorhinal cortex atrophy in community-based older adults with mild cognitive impairment (2011)
  • Author(s): Makizako H, Shimada H, Doi T, Yoshida D, Suzuki T
  • Organizer: The World Confederation for Physical Therapy
  • Place of Presentation: Amsterdam
  • Year and Date: 2011-06-23
• [Presentation] The characteristics of mobility and cognitive function in early and late stage with mild cognitive impairment (2011)
  • Author(s): Doi T, Shimada H, Makizako H, Yoshida D, Suzuki T
  • Organizer: The World Confederation for Physical Therapy
  • Place of Presentation: Amsterdam
  • Year and Date: 2011-06-23
• [Presentation] Brain activation pattern during gait in healthy elderly : An FDG PET study (2011)
  • Author(s): Shimada H, Doi T, Makizako H, Yoshida D, Suzuki T
  • Organizer: The World Confederation for Physical Therapy
  • Place of Presentation: Amsterdam
  • Year and Date: 2011-06-23
• [Presentation] Whole Brain Atrophy and Spatiotemporal Gait Parameters during Dual-task Gait (2011)
  • Author(s): Doi T, Shimada H, et al
  • Organizer: The World Confederation for Physical Therapy
  • Place of Presentation: Amsterdam
  • Year and Date: 2011-06-23
• [Presentation] 軽度認知障害高齢者に対する運動の認知機能低下抑制効果 (2011)
  • Author(s): 島田裕之
  • Organizer: RCT による検討. 第1回日本認知症予防学会学術集会
  • Place of Presentation: 米子
• [Presentation] 高齢者における嗅内野皮質周囲の萎縮と認知機能との関係 (2011)
  • Author(s): 島田裕之, 伊藤健吾, 牧迫飛雄馬, 土井剛彦, 吉田大輔, 下方浩史, 鷲見幸彦, 遠藤英俊, 鈴木隆雄
  • Organizer: 第53回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 文字流暢性課題とカテゴリー流暢性課題の課題特性 (2011)
  • Author(s): 土井剛彦, 島田裕之, 牧迫飛雄馬, 吉田大輔, 下方浩史, 伊藤健吾, 鷲見幸彦, 遠藤英俊, 鈴木隆雄
  • Organizer: 第53回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 軽度認知障害を有する高齢者のQOLと関連する要因 (2011)
  • Author(s): 牧迫飛雄馬, 島田裕之, 土井剛彦, 吉田大輔, 伊藤健吾, 下方浩史, 鷲見幸彦, 遠藤英俊, 鈴木隆雄
  • Organizer: 第53回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 認知障害と関連する日常生活活動の検討 (2011)
  • Author(s): 吉田大輔, 島田裕之, 牧迫飛雄馬, 土井剛彦, 伊藤健吾, 下方浩史, 鷲見幸彦, 遠藤英俊, 鈴木隆雄
  • Organizer: 第53回日本老年医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 認知障害を有する高齢者におけるdual-task歩行 (2011)
  • Author(s): 土井剛彦, 牧迫飛雄馬, 島田裕之, 吉田大輔, 鈴木隆雄
  • Organizer: 第1回日本基礎理学療法学会学術集会
  • Place of Presentation: 宮崎
• [Presentation] 二重課題条件下での反応時間と認知機能および脳萎縮との関連 (2011)
  • Author(s): 牧迫飛雄馬, 島田裕之, 土井剛彦, 吉田大輔, 伊藤健吾, 加藤隆司, 下方浩史, 鷲見幸彦, 遠藤英俊, 鈴木隆雄
  • Organizer: 第46回日本理学療法学術大会
  • Place of Presentation: 宮崎
• [Presentation] 高齢者における歩行指標は脳萎縮と関係するのか?-MRI と3 軸加速度計を用いた検討- (2011)
  • Author(s): 土井剛彦, 島田裕之, 牧迫飛雄馬, 吉田大輔, 伊藤健吾, 加藤隆司, 下方浩史, 鷲見幸彦, 遠藤英俊, 鈴木隆雄
  • Organizer: 第46回日本理学療法学術大会
  • Place of Presentation: 宮崎
• [Presentation] 地域高齢者における内側側頭葉の脳萎縮と日常生活活動との関係 (2011)
  • Author(s): 吉田大輔, 島田裕之, 牧迫飛雄馬, 土井剛彦, 伊藤健吾, 加藤隆司, 下方浩史, 鷲見幸彦, 遠藤英俊, 鈴木隆雄
  • Organizer: 第46回日本理学療法学術大会
  • Place of Presentation: 宮崎
• [Presentation] 歩行時の脳活動-FDG PETによる検討- (2011)
  • Author(s): 島田裕之, 鈴川芽久美, 牧迫飛雄馬, 土井剛彦, 吉田大輔, 鈴木隆雄
  • Organizer: 第46回日本理学療法学術大会
  • Place of Presentation: 宮崎
• [Book] 栄養・運動で予防するサルコペニア (2013)
  • Author(s): 島田裕之
  • Total Pages: 168
  • Publisher: 医歯薬出版
• [Book] Positron Emission Tomography - Current Clinical and Research Aspects. (2012)
  • Author(s): Shimada H
  • Total Pages: 336
  • Publisher: InTech
• [Book] 認知症予防マニュアル 記憶力の向上を目指したプログラム (2011)
  • Author(s): 鈴木隆雄 (監修), 島田裕之(編集). 牧迫飛雄馬(著者), 吉田大輔(著者), 土井剛彦(著者), 阿南祐也(著者), 堤本広大(著者), 上村一貴(著者)
  • Publisher: 東海共同印刷
• [Book] 認知症予防マニュアル記憶力の向上を目指したプログラム (2011)
  • Author(s): 島田裕之(編集)
  • Total Pages: 101
  • Publisher: 東海共同印刷
• [Remarks]
  • URL: http://www.ncgg.go.jp/department/hid/jiritsusien.html
• [Remarks] 自立支援システム開発室ホームページ
  • URL: http://www.ncgg.go.jp/department/hid/jiritsusien.html
• [Remarks]
  • URL: http://www.ncgg.go.jp/department/hid/jiritsusien.html